Anti-ARPP-19 (phospho S109) antibody - C-terminal (ab196340)
Key features and details
- Rabbit polyclonal to ARPP-19 (phospho S109) - C-terminal
- Reacts with: Xenopus tropicalis
- Isotype: IgG
Overview
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Product name
Anti-ARPP-19 (phospho S109) antibody - C-terminal
See all ARPP-19 primary antibodies -
Description
Rabbit polyclonal to ARPP-19 (phospho S109) - C-terminal -
Host species
Rabbit -
Species reactivity
Reacts with: Xenopus tropicalis -
Immunogen
Synthetic peptide corresponding to Xenopus tropicalis ARPP-19 (C terminal) (phospho S109).
Database link: Q28GU6-1 -
General notes
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Constituents: 1.21% Tris, 0.75% Glycine, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Target
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Function
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression. -
Sequence similarities
Belongs to the endosulfine family. -
Post-translational
modificationsPhosphorylation at Ser-62 by GWL during mitosis is essential for interaction with PPP2R2D (PR55-delta) and subsequent inactivation of PP2A (By similarity). Phosphorylated by PKA.
Isoform ARPP-16 contains a N-acetylmethionine at position 1. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 447957 Xenopus tropicalis
- SwissProt: Q28GU6 Xenopus tropicalis
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Alternative names
- ARP19 antibody
- ARP19_HUMAN antibody
- ARPP-19 antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab196340 has not yet been referenced specifically in any publications.