• Product name

    Anti-Artemin antibody [EPR9763]
    See all Artemin primary antibodies
  • Description

    Rabbit monoclonal [EPR9763] to Artemin
  • Host species

  • Tested applications

    Suitable for: WB, IHC-P, IPmore details
    Unsuitable for: Flow Cyt or ICC/IF
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Artemin aa 150 to the C-terminus (C terminal) (Cysteine residue). The exact sequence is proprietary.
    Database link: Q5T4W7

  • Positive control

    • Fetal brain, liver and kidney tissue lysates, T47D cell line lysate; Human cervical carcinoma tissue and Human heart tissue.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.


  • Form

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

  • Clone number

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab178434 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 23 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt or ICC/IF.
  • Target

    • Function

      Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain.
    • Tissue specificity

      Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain.
    • Sequence similarities

      Belongs to the TGF-beta family. GDNF subfamily.
    • Developmental stage

      Expressed during embryogenesis. High level expression seen in fetal kidney and lung while a low level expression seen in the fetal brain.
    • Cellular localization

    • Information by UniProt
    • Database links

    • Alternative names

      • Artemin antibody
      • Artn antibody
      • ARTN_HUMAN antibody
      • Enovin antibody
      • EVN antibody
      • NBN antibody
      • Neublastin antibody
      • Neurotrophic factor antibody
      see all


    • All lanes : Anti-Artemin antibody [EPR9763] (ab178434) at 1/1000 dilution

      Lane 1 : Fetal brain lysate
      Lane 2 : T47D cell line lysate
      Lane 3 : Fetal kidney lysate
      Lane 4 : Fetal liver lysate

      Lysates/proteins at 10 µg per lane.

      All lanes : Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution

      Developed using the ECL technique.

      Predicted band size: 23 kDa

    • Western blot analysis on immunoprecipitation pellet from (1)  fetal kidney lysate or (2) 1XPBS (negative control) using ab178434 at 1/10 dilution, and HRP-conjugated anti-rabbit IgG preferentially detecting the non-reduced form of rabbit IgG.

    • Immunohistochemical analysis of paraffin embedded Human heart tissue labeling Artemin with ab178434 at 1/50.

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    • Immunohistochemical analysis of paraffin embedded Human cervical carcinoma tissue labeling Artemin with ab178434 at 1/50.

      Perform heat mediated antigen retrieval before commencing with IHC staining protocol.


    This product has been referenced in:

    • Song Z  et al. Role of artemin in non-small cell lung cancer. Thorac Cancer 9:555-562 (2018). Read more (PubMed: 29575549) »
    • Wang J  et al. Artemin regulates CXCR4 expression to induce migration and invasion in pancreatic cancer cells through activation of NF-?B signaling. Exp Cell Res 365:12-23 (2018). Human . Read more (PubMed: 29453972) »
    See all 2 Publications for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab178434.
    Please use the links above to contact us or submit feedback about this product.

    For licensing inquiries, please contact partnerships@abcam.com

    Sign up