• Product name

  • Description

    Rabbit polyclonal to ARTS1/ERAP1
  • Host species

  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Hamster, Cow, Dog, Pig, Chimpanzee, Monkey, Gorilla, Common marmoset, Orangutan
  • Immunogen

    Synthetic peptide within Human ARTS1/ERAP1 (internal sequence). The exact sequence is proprietary. 17 aa synthetic peptide from internal region of Human ARTS1/ERAP1.
    Database link: Q9NZ08

  • Positive control

    • Human prostate and Human liver tissues.
  • General notes

     This product was previously labelled as ARTS1




Our Abpromise guarantee covers the use of ab189057 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 - 15 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.


  • Function

    Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.
  • Tissue specificity

  • Sequence similarities

    Belongs to the peptidase M1 family.
  • Post-translational

  • Cellular localization

    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • A LAP antibody
    • A-LAP antibody
    • Adipocyte derived leucine aminopeptidase antibody
    • Adipocyte-derived leucine aminopeptidase antibody
    • ALAP antibody
    • Aminopeptidase PILS antibody
    • Aminopeptidase regulator of TNFR1 shedding antibody
    • APPILS antibody
    • ARTS 1 antibody
    • ARTS-1 antibody
    • Arts1 antibody
    • Endoplasmic reticulum aminopeptidase 1 antibody
    • Endoplasmic reticulum aminopeptidase associated with antigen processing antibody
    • ERAAP antibody
    • ERAAP1 antibody
    • ERAP 1 antibody
    • Erap1 antibody
    • ERAP1_HUMAN antibody
    • KIAA0525 antibody
    • kiaa0525 protein antibody
    • PILS AP antibody
    • PILS-AP antibody
    • PILSA antibody
    • PILSAP antibody
    • Puromycin insensitive leucyl specific aminopeptidase antibody
    • Puromycin-insensitive leucyl-specific aminopeptidase antibody
    • Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator antibody
    • type 1 tumor necrosis factor receptors shedding aminopeptidase regulator antibody
    • VEGF-induced aminopeptidase antibody
    see all


  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue labeling ARTS1/ERAP1 with ab189057 at 15 µg/ml.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human prostate tissue labeling ARTS1/ERAP1 with ab189057 at 15 µg/ml.


ab189057 has not yet been referenced specifically in any publications.

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