Overview

  • Product name

    AS-605240, PI3Kgamma inhibitor
  • Description

    Potent and selective PI3Kγ inhibitor
  • Purity

    > 98%
  • CAS Number

    648450-29-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Peng XD  et al. Inhibition of phosphoinositide 3-kinase ameliorates dextran sodium sulfate-induced colitis in mice. J Pharmacol Exp Ther 332:46-56 (2010). Read more (PubMed: 19828878) »
  • Wei X  et al. A phosphoinositide 3-kinase-gamma inhibitor, AS605240 prevents bleomycin-induced pulmonary fibrosis in rats. Biochem Biophys Res Commun 397:311-7 (2010). Read more (PubMed: 20510675) »
  • Camps M  et al. Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat Med 11:936-43 (2005). Read more (PubMed: 16127437) »

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