Product nameAnti-ASAP1 / DDEF1 antibody
See all ASAP1 / DDEF1 primary antibodies
DescriptionRabbit polyclonal to ASAP1 / DDEF1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Cow
Synthetic peptide corresponding to Human ASAP1/ DDEF1 (C terminal).
Database link: Q9ULH1
- WB: ASAP1 / DDEF1-transfected U118 cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 0.87% Sodium chloride, 0.42% Potassium phosphate
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab263968 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 125 kDa.|
FunctionPossesses phosphatidylinositol 4,5-biphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity). Plays a role in ciliogenesis.
Sequence similaritiesContains 2 ANK repeats.
Contains 1 Arf-GAP domain.
Contains 1 PH domain.
Contains 1 SH3 domain.
DomainThe PH domain most probably contributes to the phosphoinositide-dependent regulation of ADP ribosylation factors.
modificationsPhosphorylated on tyrosine residues by SRC.
Cellular localizationCytoplasm. Membrane. Predominantly cytoplasmic (By similarity). Partially membrane-associated.
- Information by UniProt
- 130 kDa phosphatidylinositol 4 5 biphosphate dependent ARF1 GTPase activating protein antibody
- 130 kDa phosphatidylinositol 4 antibody
- 5-biphosphate-dependent ARF1 GTPase-activating protein antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab263968 has not yet been referenced specifically in any publications.