Key features and details
- Rabbit polyclonal to ASAP1 / DDEF1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ASAP1 / DDEF1 antibody
See all ASAP1 / DDEF1 primary antibodies
DescriptionRabbit polyclonal to ASAP1 / DDEF1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
Recombinant fragment corresponding to Human ASAP1/ DDEF1 aa 912-1115.
DKATIPPEIFQKSSQLAELPQKPPPGDLPPKPTELAPKPQIGDLPPKPGE LPPKPQLGDLPPKPQLSDLPPKPQMKDLPPKPQLGDLLAKSQTGDVSPKA QQPSEVTLKSHPLDLSPNVQSRDAIQKQASEDSNDLTPTLPETPVPLPRK INTGKNKVRRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEG QPER
Database link: Q9ULH1
- Pancreas lysate
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.05% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab208170 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 4 µg/ml. Predicted molecular weight: 125 kDa.|
FunctionPossesses phosphatidylinositol 4,5-biphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity). Plays a role in ciliogenesis.
Sequence similaritiesContains 2 ANK repeats.
Contains 1 Arf-GAP domain.
Contains 1 PH domain.
Contains 1 SH3 domain.
DomainThe PH domain most probably contributes to the phosphoinositide-dependent regulation of ADP ribosylation factors.
modificationsPhosphorylated on tyrosine residues by SRC.
Cellular localizationCytoplasm. Membrane. Predominantly cytoplasmic (By similarity). Partially membrane-associated.
- Information by UniProt
- 130 kDa phosphatidylinositol 4 5 biphosphate dependent ARF1 GTPase activating protein antibody
- 130 kDa phosphatidylinositol 4 antibody
- 5-biphosphate-dependent ARF1 GTPase-activating protein antibody
ab208170 has not yet been referenced specifically in any publications.