Overview

  • Product name

  • Description

    Rabbit polyclonal to ASC1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Chimpanzee, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human ASC1 (internal sequence). The exact sequence is proprietary.
    Database link: Q15650

  • Positive control

    • WB: Neuro-2a, GL261, C8D30, NIH/3T3, BCL-1 and RAW 264.7 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab228630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 66 kDa.

Target

  • Function

    Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function.
  • Cellular localization

    Nucleus. Cytoplasm. Cytoplasmic under conditions of serum deprivation.
  • Information by UniProt
  • Database links

  • Alternative names

    • Activating signal cointegrator 1 antibody
    • ASC 1 antibody
    • ASC-1 antibody
    • HsT17391 antibody
    • Thyroid hormone receptor interactor 4 antibody
    • Thyroid receptor interacting protein 4 antibody
    • Thyroid receptor-interacting protein 4 antibody
    • TR-interacting protein 4 antibody
    • TRIP 4 antibody
    • TRIP-4 antibody
    • Trip4 antibody
    • TRIP4_HUMAN antibody
    • ZC2HC5 antibody
    • Zinc finger C2HC5 type antibody
    see all

Images

  • All lanes : Anti-ASC1 antibody (ab228630) at 1/1000 dilution

    Lane 1 : Neuro-2a (mouse neuroblastoma cell line) whole cell lysate
    Lane 2 : GL261 (mouse glioma cell line) whole cell lysate
    Lane 3 : C8D30 (mouse astrocyte) whole cell lysate
    Lane 4 : NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate
    Lane 5 : BCL-1 (mouse leukemia cell line) whole cell lysate
    Lane 6 : RAW 264.7 (mouse macrophage cell line transformed with Abelson murine leukemia virus) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 66 kDa



    7.5% SDS-PAGE

References

ab228630 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228630.
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