Overview

  • Product name

    Anti-Asialoglycoprotein Receptor 1/HL-1 antibody
    See all Asialoglycoprotein Receptor 1/HL-1 primary antibodies
  • Description

    Rabbit polyclonal to Asialoglycoprotein Receptor 1/HL-1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment corresponding to Human Asialoglycoprotein Receptor 1/HL-1 aa 25-241.
    Database link: P07306

  • Positive control

    • Human HepG2 and Mouse NIH 3T3 cell lysates.
  • General notes

    Previously labelled as Asialoglycoprotein Receptor 1. 

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.025% Proclin
    Constituents: PBS, 1% BSA, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab127896 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 33 kDa.

Target

  • Function

    Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
  • Tissue specificity

    Expressed exclusively in hepatic parenchymal cells.
  • Sequence similarities

    Contains 1 C-type lectin domain.
  • Post-translational
    modifications

    Phosphorylated on a cytoplasmic Ser residue.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ASGP-R 1 antibody
    • ASGPR 1 antibody
    • ASGPR antibody
    • ASGPR1 antibody
    • Asgr1 antibody
    • ASGR1_HUMAN antibody
    • Asialoglycoprotein receptor 1 antibody
    • C type lectin domain family 4 member H1 antibody
    • C-type lectin domain family 4 member H1 antibody
    • CLEC4H1 antibody
    • Hepatic lectin H1 antibody
    • HL-1 antibody
    see all

Images

  • Anti-Asialoglycoprotein Receptor 1/HL-1 antibody (ab127896) at 1/3000 dilution + HepG2 whole cell lysate at 30 µg

    Developed using the ECL technique.

    Predicted band size: 33 kDa



    12% SDS Page
  • Anti-Asialoglycoprotein Receptor 1/HL-1 antibody (ab127896) at 1/1000 dilution + Mouse NIH 3T3 whole cell lysate at 30 µg

    Developed using the ECL technique.

    Predicted band size: 33 kDa



    12% SDS Page

References

ab127896 has not yet been referenced specifically in any publications.

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