Product nameAstaxanthin, Antioxidant agent
DescriptionPotent antioxidant agent. PPARα agonist and PPARγ antagonist.
Biological descriptionPotent antioxidant agent. PPARα agonist and PPARγ antagonist. Free radical scavenger. Reduces oxidative stress. Induces apoptosis. Inhibits NF-κB. Shows anti-inflammatory, antihypertensive, cardioprotective, neuroprotective and antitumor effects in vivo. Orally active.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol (with heating) and in DMSO
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Signal transduction
- Nitric oxide & oxidative stress
This product has been referenced in:
- Song X et al. Astaxanthin inhibits apoptosis in alveolar epithelial cells type II in vivo and in vitro through the ROS-dependent mitochondrial signalling pathway. J Cell Mol Med : (2014). Read more (PubMed: 25215580) »
- Jia Y et al. The natural carotenoid astaxanthin, a PPAR-a agonist and PPAR-? antagonist, reduces hepatic lipid accumulation by rewiring the transcriptome in lipid-loaded hepatocytes. Mol Nutr Food Res 56:878-88 (2012). Read more (PubMed: 22707263) »
- Inoue M et al. Astaxanthin functions differently as a selective peroxisome proliferator-activated receptor ? modulator in adipocytes and macrophages. Biochem Pharmacol 84:692-700 (2012). Read more (PubMed: 22732454) »