Product nameAstilbin, flavonoid found in plants
DescriptionAntioxidant. Anti-inflammatory agent.
Biological descriptionAntioxidant. Anti-inflammatory agent. Increases IL-10 and TGF-β serum levels. Shows central effects. Increases brain 5-HT and dopamine levels. Activates BDNF signaling pathway. Shows antidepressant, anti-inflammatory and antioxidant effects in vivo. Orally active.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Signal transduction
- Nitric oxide & oxidative stress
This product has been referenced in:
- Christopher R et al. A new cinnamoylglycoflavonoid, antimycobacterial and antioxidant constituents from Heritiera littoralis leaf extracts. Nat Prod Res 28:351-8 (2014). Read more (PubMed: 24443810) »
- Ding Y et al. Induction of TGF-ß and IL-10 production in dendritic cells using astilbin to inhibit dextran sulfate sodium-induced colitis. Biochem Biophys Res Commun 446:529-34 (2014). Read more (PubMed: 24613838) »
- Lv QQ et al. Antidepressant activity of astilbin: involvement of monoaminergic neurotransmitters and BDNF signal pathway. Biol Pharm Bull 37:987-95 (2014). Read more (PubMed: 24681540) »