Product nameAnti-ATF-4 antibody
See all ATF-4 primary antibodies
DescriptionRabbit polyclonal to ATF-4
SpecificityAntibody detects endogenous levels of ATF-4 protein around Serine 245.
Tested applicationsSuitable for: ICC/IF, IHC-Fr, IHC-P, ELISAmore details
Species reactivityReacts with: Mouse, Human
Synthetic peptide corresponding to Human ATF-4.
Database link: P18848
- Breast carcinoma tissue.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol, 0.87% Sodium chloride
Without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Corresponding phospho antibody
Our Abpromise guarantee covers the use of ab31390 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use at an assay dependent concentration. PubMed: 21933012Fixed with methanol|
|IHC-Fr||Use at an assay dependent concentration.|
|IHC-P||Use at an assay dependent concentration.|
FunctionTranscriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I.
Sequence similaritiesBelongs to the bZIP family.
Contains 1 bZIP domain.
Cellular localizationCytoplasm. Cell membrane. Nucleus. Colocalizes with GABBR1 in hippocampal neuron dendritic membranes.
- Information by UniProt
- Activating transcription factor 4 antibody
- ATF 4 antibody
- ATF4 antibody
This product has been referenced in:
- Liu P et al. Crizotinib-induced immunogenic cell death in non-small cell lung cancer. Nat Commun 10:1486 (2019). Read more (PubMed: 30940805) »
- Zheng C et al. Suppressing UPR-dependent overactivation of FGFR3 signaling ameliorates SLC26A2-deficient chondrodysplasias. EBioMedicine 40:695-709 (2019). Read more (PubMed: 30685387) »