Key features and details
- Rabbit polyclonal to ATF-4 (phospho S245)
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ATF-4 (phospho S245) antibody
See all ATF-4 primary antibodies
DescriptionRabbit polyclonal to ATF-4 (phospho S245)
Specificityab28830 recognizes Phospho-ATF-4(Ser245).
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human ATF-4.
Database link: P18848
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Concentration information loading...
PurityImmunogen affinity purified
Corresponding non-phospho antibody
Our Abpromise guarantee covers the use of ab28830 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/100.|
FunctionTranscriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I.
Sequence similaritiesBelongs to the bZIP family.
Contains 1 bZIP domain.
Cellular localizationCytoplasm. Cell membrane. Nucleus. Colocalizes with GABBR1 in hippocampal neuron dendritic membranes.
- Information by UniProt
- Activating transcription factor 4 antibody
- ATF 4 antibody
- ATF4 antibody
ab28830 has been referenced in 4 publications.
- González-González A et al. Activating Transcription Factor 4 Modulates TGFß-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling. Clin Cancer Res 24:5697-5709 (2018). PubMed: 30012564
- El-Khattouti A et al. Imiquimod-induced apoptosis of melanoma cells is mediated by ER stress-dependent Noxa induction and enhanced by NF-?B inhibition. J Cell Mol Med 20:266-86 (2016). WB . PubMed: 26578344
- Kalamida D et al. Important role of autophagy in endothelial cell response to ionizing radiation. PLoS One 9:e102408 (2014). WB ; Human . PubMed: 25010689
- Myers SA et al. CD36 deletion improves recovery from spinal cord injury. Exp Neurol 256:25-38 (2014). PubMed: 24690303