Key features and details
- Rabbit polyclonal to ATF3
- Suitable for: WB, IHC-P
- Reacts with: Mouse
- Isotype: IgG
Product nameAnti-ATF3 antibody
See all ATF3 primary antibodies
DescriptionRabbit polyclonal to ATF3
Tested applicationsSuitable for: WB, IHC-Pmore details
Unsuitable for: ICC/IF
Species reactivityReacts with: Mouse
Predicted to work with: Rat, Cow, Human
- Skeletal Muscle (Mouse) Whole Cell Lysate (ab3869) can be used as a positive control in WB. Mouse heart cell lysate; Mouse skeletal muscle cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab180842 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Predicted molecular weight: 21 kDa.|
|IHC-P||1/50 - 1/200.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
FunctionThis protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Sequence similaritiesBelongs to the bZIP family. ATF subfamily.
Contains 1 bZIP domain.
- Information by UniProt
- Activating transcription factor 3 antibody
- ATF3 antibody
- ATF3_HUMAN antibody
ab180842 has been referenced in 2 publications.
- Cho E et al. PSTP-3,5-Me Inhibits Osteoclast Differentiation and Bone Resorption. Molecules 24:N/A (2019). PubMed: 31540026
- Lee S et al. ATF3 Stimulates IL-17A by Regulating Intracellular Ca2+/ROS-Dependent IL-1ß Activation During Streptococcus pneumoniae Infection. Front Immunol 9:1954 (2018). PubMed: 30214444