• Product name

    Anti-ATF7 antibody [EPR13556]
    See all ATF7 primary antibodies
  • Description

    Rabbit monoclonal [EPR13556] to ATF7
  • Host species

  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human ATF7 aa 1-100. The exact sequence is proprietary.
    Database link: P17544

  • Positive control

    • Raji, C6, Raw 264.7 and PC-12 cell lysates
  • General notes



    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.



Our Abpromise guarantee covers the use of ab183507 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 53 kDa.


  • Function

    Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.
    Isoform 4/ATF-A0 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter.
  • Tissue specificity

    Expressed in heart, lung and skeletal muscle. Isoform 4 is expressed in various tissues including heart, brain, placenta, lung and skeletal muscle. Highest levels in skeletal muscle. Lowest in lung and placenta.
  • Sequence similarities

    Belongs to the bZIP family.
    Contains 1 bZIP domain.
    Contains 1 C2H2-type zinc finger.
  • Post-translational

    On EGF stimulation, phosphorylated first on Thr-53 allowing subsequent phosphorylation on Thr-51. This latter phosphorylation prevents sumoylation, increases binding to TAF12 and enhances transcriptional activity.
    Sumoylation delays nuclear localization and inhibits transactivation activity through preventing binding to TAF12. RANBP2 appears to be the specific E3 ligase.
  • Cellular localization

    Nucleus. Nucleus > nucleoplasm. Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear periphery.
  • Information by UniProt
  • Database links

  • Alternative names

    • 1110012F10Rik antibody
    • 9430065F09Rik antibody
    • Activating transcription factor 7 antibody
    • AI549878 antibody
    • ATF7 antibody
    • Atf7 protein antibody
    • ATF7_HUMAN antibody
    • ATFA antibody
    • C130020M04Rik antibody
    • cAMP-dependent transcription factor ATF-7 antibody
    • Cyclic AMP-dependent transcription factor ATF 7 antibody
    • Cyclic AMP-dependent transcription factor ATF-7 antibody
    • MGC31554 antibody
    • MGC57182 antibody
    • Transcription factor ATF A antibody
    • Transcription factor ATF-A antibody
    see all


  • Anti-ATF7 antibody [EPR13556] (ab183507) at 1/1000 dilution + Raji cell lysate at 20 µg

    Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

    Predicted band size: 53 kDa

  • All lanes : Anti-ATF7 antibody [EPR13556] (ab183507) at 1/1000 dilution

    Lane 1 : C6 cell lysate
    Lane 2 : Raw 264.7 cell lysate
    Lane 3 : PC-12 cell lysate

    Lysates/proteins at 10 µg per lane.

    All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

    Predicted band size: 53 kDa


ab183507 has not yet been referenced specifically in any publications.

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