Overview

  • Product name

    Anti-ATG4C antibody - C-terminal
    See all ATG4C primary antibodies
  • Description

    Rabbit polyclonal to ATG4C - C-terminal
  • Host species

    Rabbit
  • Specificity

    ab191705 is predicted to not cross-react with other ATG4 proteins.
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human ATG4C (C terminal). An 18 amino acid peptide near the carboxy terminus of Human ATG4C. NP_835739.
    Database link: Q96DT6

  • Positive control

    • A549 cell lysate. Human lung tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab191705 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 57 kDa (predicted molecular weight: 52 kDa).
IHC-P Use a concentration of 5 - 20 µg/ml.

Target

  • Function

    Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
  • Tissue specificity

    Highly expressed in skeletal muscle, heart, liver and testis.
  • Sequence similarities

    Belongs to the peptidase C54 family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • APG4 autophagy 4 homolog C (S. cerevisiae) antibody
    • APG4 autophagy 4 homolog C antibody
    • APG4 C antibody
    • APG4-C antibody
    • APG4C antibody
    • ATG 4C antibody
    • ATG4 autophagy related 4 homolog C (S. cerevisiae) antibody
    • ATG4 autophagy related 4 homolog C antibody
    • Atg4c antibody
    • ATG4C_HUMAN antibody
    • AUT (S. cerevisiae) like 1, cysteine endopeptidase antibody
    • AUT like 1, cysteine endopeptidase (S. cerevisiae) antibody
    • AUT like 1, cysteine endopeptidase antibody
    • AUT like 3 cysteine endopeptidase antibody
    • AUT-like 3 cysteine endopeptidase antibody
    • AUTL1 antibody
    • AUTL3 antibody
    • Autophagin 3 antibody
    • Autophagin-3 antibody
    • Autophagy related 4C cysteine peptidase antibody
    • Autophagy related cysteine endopeptidase 3 antibody
    • Autophagy related protein 4 homolog C antibody
    • Autophagy-related cysteine endopeptidase 3 antibody
    • Autophagy-related protein 4 homolog C antibody
    • Cysteine protease ATG4C antibody
    • EC 3.4.22 antibody
    • FLJ14867 antibody
    • OTTHUMP00000010715 antibody
    see all

Images

  • Anti-ATG4C antibody - C-terminal (ab191705) at 1 µg/ml + A549 cell lysate at 15 µg

    Predicted band size: 52 kDa

  • Immunofluorescent analysis of human lung tissue labeling ATG4C with ab181391 at 20 µg/ml

  • Immunohistochemical analysis of human lung tissue labeling ATG4C with ab191705 at 5 µg/ml.

References

ab191705 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191705.
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