Validated using a knockout cell line

Recombinant Anti-ATG9A antibody [EPR2450(2)] (ab108338)

Knockout Tested Rabbit recombinant monoclonal ATG9A antibody [EPR2450(2)]. Validated in WB, IP, IHC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Human. Cited in 21 publication(s).

Publishing research using ab108338? Please let us know so that we can cite the reference in this datasheet.

ab108338 has been referenced in 22 publications.

  • Qiu S  et al. The blockade of lipophagy pathway is necessary for docosahexaenoic acid to regulate lipid droplet turnover in hepatic stellate cells. Biomed Pharmacother 109:1841-1850 (2019). PubMed: 30551439
  • Claude-Taupin A  et al. ATG9A Is Overexpressed in Triple Negative Breast Cancer and Its In Vitro Extinction Leads to the Inhibition of Pro-Cancer Phenotypes. Cells 7:N/A (2018). PubMed: 30563263
  • Heo JM  et al. RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway. Sci Adv 4:eaav0443 (2018). PubMed: 30627666
  • Jiang CY  et al. Deregulation of ATG9A by impaired AR signaling induces autophagy in prostate stromal fibroblasts and promotes BPH progression. Cell Death Dis 9:431 (2018). PubMed: 29568063
  • Jimenez-Orgaz A  et al. Control of RAB7 activity and localization through the retromer-TBC1D5 complex enables RAB7-dependent mitophagy. EMBO J 37:235-254 (2018). Human . PubMed: 29158324
  • Søreng K  et al. SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin-2. EMBO Rep 19:N/A (2018). ICC/IF ; Human . PubMed: 29437695
  • De Pace R  et al. Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome. PLoS Genet 14:e1007363 (2018). PubMed: 29698489
  • Pavel M  et al. Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis. Nat Commun 9:2961 (2018). PubMed: 30054475
  • Zhou C  et al. Regulation of mATG9 trafficking by Src- and ULK1-mediated phosphorylation in basal and starvation-induced autophagy. Cell Res 27:184-201 (2017). PubMed: 27934868
  • Goodwin JM  et al. Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9. Cell Rep 20:2341-2356 (2017). ICC/IF ; Human . PubMed: 28877469
  • Merrill NM  et al. PI3K-C2a knockdown decreases autophagy and maturation of endocytic vesicles. PLoS One 12:e0184909 (2017). PubMed: 28910396
  • Nunes J  et al. ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation. Oncotarget 7:27599-612 (2016). PubMed: 27050377
  • Cao QH  et al. Prognostic value of autophagy related proteins ULK1, Beclin 1, ATG3, ATG5, ATG7, ATG9, ATG10, ATG12, LC3B and p62/SQSTM1 in gastric cancer. Am J Transl Res 8:3831-3847 (2016). PubMed: 27725863
  • Wu X  et al. Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun 7:10533 (2016). ICC/IF ; Human . PubMed: 26837467
  • Moreau K  et al. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. Nat Commun 6:8045 (2015). ICC/IF ; Human . PubMed: 26289944
  • Moreau K  et al. Methods to analyze SNARE-dependent vesicular fusion events that regulate autophagosome biogenesis. Methods 75:19-24 (2015). PubMed: 25461811
  • Soo KY  et al. ALS-associated mutant FUS inhibits macroautophagy which is restored by overexpression of Rab1. Cell Death Discov 1:15030 (2015). PubMed: 27551461
  • Zavodszky E  et al. Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy. Nat Commun 5:3828 (2014). ICC/IF ; Human . PubMed: 24819384
  • Uemura T  et al. A cluster of thin tubular structures mediates transformation of the endoplasmic reticulum to autophagic isolation membrane. Mol Cell Biol 34:1695-706 (2014). PubMed: 24591649
  • Mitzel DN  et al. Age-enhanced endoplasmic reticulum stress contributes to increased Atg9A inhibition of STING-mediated IFN-ß production during Streptococcus pneumoniae infection. J Immunol 192:4273-83 (2014). PubMed: 24670807
  • Moreau K  et al. PICALM modulates autophagy activity and tau accumulation. Nat Commun 5:4998 (2014). ICC/IF ; Human . PubMed: 25241929
  • Puri C  et al. Diverse autophagosome membrane sources coalesce in recycling endosomes. Cell 154:1285-99 (2013). PubMed: 24034251

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