Key features and details
- Selective α2 adrenoceptor antagonist
- CAS Number: 104075-48-1
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameAtipamezole hydrochloride, alpha2 adrenoceptor antagonist
DescriptionSelective α2 adrenoceptor antagonist
Selective α2 adrenoceptor antagonist. Ki values for receptor subtypes are 1.1 (α2A), 1.0 (α2B), 0.89 (α2C), 1300 (α1A) and 8500 nM (α1B). Centrally active following peripheral administration.
Chemical name5-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole hydrochloride
Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120785 has been referenced in 1 publication.
- Tyurin-Kuzmin PA et al. Activation of ß-adrenergic receptors is required for elevated a1A-adrenoreceptors expression and signaling in mesenchymal stromal cells. Sci Rep 6:32835 (2016). PubMed: 27596381