Key features and details
- Rabbit polyclonal to ATMIN
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ATMIN antibody
See all ATMIN primary antibodies
DescriptionRabbit polyclonal to ATMIN
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Recombinant fragment corresponding to Human ATMIN aa 595-768. This sequence corresponds to aa 650-823 of reviewed Uniprot entry O43313.
QTEESELSTMTTEPVLESLDIETQTDFLLADTSAQSYGCRGNSNFLGLEM FDTQTQTDLNFFLDSSPHLPLGSILKHSSFSVSTDSSDTETQTEGVSTAK NIPALESKVQLNSTETQTMSSGFETLGSLFFTSNETQTAMDDFLLADLAW NTMESQFSSVETQTSAEPHTVSNF
Database link: BC002701
- WB: Jurkat, HeLa, HepG2, K562 and A549 cell lysates and human fetal kidney tissue lysate. IHC-P: Breast carcinoma tissue.
FormLyophilized:200 µl Steriled Distilled Water
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab176894 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/200 - 1/1000. Predicted molecular weight: 88 kDa.|
|IHC-P||1/100 - 1/500.|
FunctionPlays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM.
Tissue specificityUbiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle.
Sequence similaritiesContains 2 C2H2-type zinc fingers.
Cellular localizationNucleus. Nuclear, in discrete foci during G1 phase.
- Information by UniProt
- ASCIZ antibody
- ATM INteracting protein antibody
- ATM interactor antibody
Immunohistochemical analysis of formalin fixed paraffin-embedded breast carcinoma tissue labeling ATMIN with ab176894 at 1/100 dilution.
All lanes : Anti-ATMIN antibody (ab176894) at 1/500 dilution
Lane 1 : Jurkat lysate
Lane 2 : HeLa lysate
Lane 3 : HepG2 lysate
Lane 4 : K562 lysate
Lane 5 : A549 lysate
Lane 6 : Human fetal kidney tissue lysate
Developed using the ECL technique.
Predicted band size: 88 kDa
ab176894 has not yet been referenced specifically in any publications.