Overview

  • Product name

    Anti-ATMIN antibody - N-terminal
    See all ATMIN primary antibodies
  • Description

    Rabbit polyclonal to ATMIN - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, ICC, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human ATMIN (N terminal). (19 amino acid peptide from near the amino terminus; NP_056066).
    Database link: O43313

  • Positive control

    • WB: 293 cell lysate. ICC/IF: A431 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab191856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 2.5 µg/ml.
ICC Use a concentration of 5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 72 kDa (predicted molecular weight: 88, 72 kDa).

Target

  • Function

    Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM.
  • Tissue specificity

    Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle.
  • Sequence similarities

    Contains 2 C2H2-type zinc fingers.
  • Cellular localization

    Nucleus. Nuclear, in discrete foci during G1 phase.
  • Information by UniProt
  • Database links

  • Alternative names

    • ASCIZ antibody
    • ATM INteracting protein antibody
    • ATM interactor antibody
    • ATM substrate CHK2-interacting zinc finger protein antibody
    • ATM/ATR substrate CHEK2 interacting zinc finger protein antibody
    • ATM/ATR Substrate Chk2 Interacting Zn++ finger protein antibody
    • ATM/ATR substrate Chk2 interacting Zn2+ finger protein antibody
    • ATM/ATR-substrate CHK2-interacting zinc finger protein antibody
    • ATMIN antibody
    • ATMIN_HUMAN antibody
    • DKFZp779K1455 antibody
    • FLJ76795 antibody
    • KIAA0431 antibody
    • Zinc finger protein 822 antibody
    • ZNF 822 antibody
    • ZNF822 antibody
    see all

Images

  • Lane 1 : Anti-ATMIN antibody - N-terminal (ab191856) at 1 µg/ml
    Lane 2 : Anti-ATMIN antibody - N-terminal (ab191856) at 2 µg/ml

    All lanes : 293 cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 88, 72 kDa
    Observed band size: 72 kDa
    why is the actual band size different from the predicted?

  • Immunofluorescent analysis of A431 cells labeling ATMIN with ab191856 at 2.5 μg/ml.

  • Immunocytochemical analysis of A431 cells labeling ATMIN with ab191856 at 5 μg/ml.

References

ab191856 has not yet been referenced specifically in any publications.

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