Overview

  • Product name

    Anti-ATOH8 antibody
  • Description

    Rabbit polyclonal to ATOH8
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human ATOH8 (C terminal).
    Database link: NP_116216

  • Positive control

    • A-20 cell lysate; Mouse brain tissue.
  • General notes

     This product was previously labelled as Protein atonal homolog 8

     

Properties

Applications

Our Abpromise guarantee covers the use of ab106377 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 35 kDa.
IHC-P Use at an assay dependent concentration.

Target

  • Function

    Putative transcription factor. May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation.
  • Tissue specificity

    Expressed in lung, liver, kidney, heart and pancreas. Expressed in endothel of umbilical vessels.
  • Sequence similarities

    Contains 1 basic helix-loop-helix (bHLH) domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Form

    Putative transcription factor. May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. Efficient DNA binding requires dimerization with another bHLH protein. Contains 1 basic helix-loop-helix (bHLH) domain. Cellular localisation: nucleus.
  • Alternative names

    • 4933425C05Rik antibody
    • ATOH8 antibody
    • ATOH8_HUMAN antibody
    • Atonal homolog 6 antibody
    • atonal homolog 8 (Drosophila) antibody
    • Atonal homolog 8 antibody
    • Basic helix loop helix transcription factor 6 antibody
    • bHLHa21 antibody
    • Class A basic helix-loop-helix protein 21 antibody
    • FLJ14708 antibody
    • FLJ38730 antibody
    • hATH6 antibody
    • Helix loop helix protein mATH-6 antibody
    • Helix-loop-helix protein hATH-6 antibody
    • Math6 antibody
    • Okadin antibody
    • Protein atonal homolog 8 antibody
    • RGD1561512 antibody
    see all

Images

  • Lane 1 : Anti-ATOH8 antibody (ab106377) at 1 µg/ml
    Lane 2 : Anti-ATOH8 antibody (ab106377) at 2 µg/ml

    All lanes : A-20 cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 35 kDa

References

This product has been referenced in:

  • Wang Z  et al. Downregulation of ATOH8 induced by EBV-encoded LMP1 contributes to the malignant phenotype of nasopharyngeal carcinoma. Oncotarget 7:26765-79 (2016). WB . Read more (PubMed: 27049918) »
  • Fang F  et al. The role of Hath6, a newly identified shear-stress-responsive transcription factor, in endothelial cell differentiation and function. J Cell Sci 127:1428-40 (2014). WB ; Human . Read more (PubMed: 24463812) »
See all 2 Publications for this product

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