Key features and details
- Potent, selective, competitive norepinephrine reuptake inhibitor
- CAS Number: 82857-40-7
- Form / State: Solid
- Source: Synthetic
Product nameAtomoxetine Hydrochloride (Tomoxetine hydrochloride), norepinephrine reuptake inhibitor
DescriptionPotent, selective, competitive norepinephrine reuptake inhibitor
Biological descriptionPotent, selective, competitive norepinephrine reuptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). Decreases glutamatergic transmission in a brain region-specific manner. Shows psychostimulant and appetite suppressant effects in vivo. Blood-brain barrier permeable. Orally active.
Chemical nameN-Methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine hydrochloride
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144699 has not yet been referenced specifically in any publications.