Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR14137] to ATP1A3 - N-terminal
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Product nameAnti-ATP1A3 antibody [EPR14137] - N-terminal
See all ATP1A3 primary antibodies
DescriptionRabbit monoclonal [EPR14137] to ATP1A3 - N-terminal
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
- Mouse and rat brain lysate. Human fetal brain lysate. Human hippocampus tissue lysate.
This product was previously labelled as alpha 3 Sodium Potassium ATPase
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 59% PBS, 0.05% BSA, 40% Glycerol
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab182572 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Detects a band of approximately 100-150 kDa (predicted molecular weight: 111 kDa).|
FunctionThis is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Involvement in diseaseDystonia 12
Alternating hemiplegia of childhood 2
Cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss
Sequence similaritiesBelongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
Cellular localizationCell membrane.
- Information by UniProt
- AHC2 antibody
- Alpha(III) antibody
- AT1A3_HUMAN antibody
All lanes : Anti-ATP1A3 antibody [EPR14137] - N-terminal (ab182572) at 1/5000 dilution
Lane 1 : Mouse brain lysate
Lane 2 : Rat brain lysate
Lane 3 : Human fetal brain lysate
Lane 4 : Human hippocampus lysate
Lysates/proteins at 20 µg per lane.
All lanes : Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution
Predicted band size: 111 kDa
The 150 KDa band is caused by glycosylation which is consistent with what has been described in PMID: 22797008.
ab182572 has not yet been referenced specifically in any publications.