Anti-ATP5A antibody [15H4C4] - Mitochondrial Marker (ab14748)

Mouse monoclonal ATP5A antibody [15H4C4]. Validated in WB, IP, IHC, ICC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Cow, Human, Pig, Caenorhabditis elegans, Drosophila melanogaster, Monkey.

Publishing research using ab14748? Please let us know so that we can cite the reference in this datasheet.

ab14748 has been referenced in 205 publications.

  • Gentric G  et al. PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers. Cell Metab 29:156-173.e10 (2019). PubMed: 30244973
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  • Wang H  et al. ?-Tocotrienol inhibits oxidative phosphorylation and triggers apoptosis by inhibiting mitochondrial complex I subunit NDUFB8 and complex II subunit SDHB. Toxicology 417:42-53 (2019). PubMed: 30769052
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  • Spangenberg L  et al. Deep sequencing discovery of causal mtDNA mutations in a patient with unspecific neurological disease. Mitochondrion 46:337-344 (2019). PubMed: 30227252
  • Tufi R  et al. Comprehensive Genetic Characterization of Mitochondrial Ca2+ Uniporter Components Reveals Their Different Physiological Requirements In Vivo. Cell Rep 27:1541-1550.e5 (2019). PubMed: 31042479
  • Tseng CC  et al. Rhodoptilometrin, a Crinoid-Derived Anthraquinone, Induces Cell Regeneration by Promoting Wound Healing and Oxidative Phosphorylation in Human Gingival Fibroblast Cells. Mar Drugs 17:N/A (2019). PubMed: 30818790
  • Liu HW  et al. Exercise training upregulates SIRT1 to attenuate inflammation and metabolic dysfunction in kidney and liver of diabetic db/db mice. Nutr Metab (Lond) 16:22 (2019). PubMed: 30988688
  • Potes Y  et al. Overweight in the Elderly Induces a Switch in Energy Metabolism that Undermines Muscle Integrity. Aging Dis 10:217-230 (2019). PubMed: 31011474
  • García-Roche M  et al. Impaired hepatic mitochondrial function during early lactation in dairy cows: Association with protein lysine acetylation. PLoS One 14:e0213780 (2019). PubMed: 30870481
  • Wali JA  et al. Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice. Cell Death Differ 25:217-225 (2018). PubMed: 29053141
  • Straub IR  et al. Loss of CHCHD10-CHCHD2 complexes required for respiration underlies the pathogenicity of a CHCHD10 mutation in ALS. Hum Mol Genet 27:178-189 (2018). PubMed: 29121267
  • O'Rourke AR  et al. Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms. FEBS J 285:481-500 (2018). PubMed: 29265728
  • Saita S  et al. PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. EMBO J 37:N/A (2018). PubMed: 29301859
  • Chen XF  et al. Effect of puerarin in promoting fatty acid oxidation by increasing mitochondrial oxidative capacity and biogenesis in skeletal muscle in diabetic rats. Nutr Diabetes 8:1 (2018). PubMed: 29330446
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  • Cao K  et al. Quantitative Analysis of Seven New Prostate Cancer Biomarkers and the Potential Future of the 'Biomarker Laboratory'. Diagnostics (Basel) 8:N/A (2018). PubMed: 30060509
  • Song KH  et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest 128:4098-4114 (2018). PubMed: 30124467
  • Quintana-Cabrera R  et al. The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function. Nat Commun 9:3399 (2018). PubMed: 30143614
  • Du Y  et al. SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice. EBioMedicine 36:347-357 (2018). PubMed: 30279144
  • Yardeni T  et al. High content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria. Sci Rep 8:59 (2018). PubMed: 29311649
  • Agnew T  et al. MacroD1 Is a Promiscuous ADP-Ribosyl Hydrolase Localized to Mitochondria. Front Microbiol 9:20 (2018). PubMed: 29410655
  • Zhou C  et al. Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth. Cell Death Dis 9:161 (2018). WB . PubMed: 29415987
  • Goldberg J  et al. The mitochondrial ATP synthase is a shared drug target for aging and dementia. Aging Cell 17:N/A (2018). WB ; Mouse . PubMed: 29316249
  • Lim SC  et al. Loss of the Mitochondrial Fatty Acid ß-Oxidation Protein Medium-Chain Acyl-Coenzyme A Dehydrogenase Disrupts Oxidative Phosphorylation Protein Complex Stability and Function. Sci Rep 8:153 (2018). WB ; Human . PubMed: 29317722
  • Marrone L  et al. Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease. PLoS One 13:e0192497 (2018). PubMed: 29513666
  • Lee JJ  et al. Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin. J Cell Biol 217:1613-1622 (2018). PubMed: 29500189
  • Becker C  et al. CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis. EMBO Rep 19:N/A (2018). PubMed: 29588285
  • Krysciak K  et al. Adaptation of motor unit contractile properties in rat medial gastrocnemius to treadmill endurance training: Relationship to muscle mitochondrial biogenesis. PLoS One 13:e0195704 (2018). PubMed: 29672614
  • Lehmer C  et al. A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS. EMBO Mol Med 10:N/A (2018). WB, ICC/IF . PubMed: 29789341
  • Pittala S  et al. Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide. Neoplasia 20:594-609 (2018). IHC-P ; Mouse . PubMed: 29747160
  • Lu Y  et al. Mitophagy is required for brown adipose tissue mitochondrial homeostasis during cold challenge. Sci Rep 8:8251 (2018). PubMed: 29844467
  • Bezawork-Geleta A  et al. Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints. Nat Commun 9:2221 (2018). PubMed: 29880867
  • Ludtmann MHR  et al. a-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease. Nat Commun 9:2293 (2018). ICC/IF . PubMed: 29895861
  • Vagnoni A & Bullock SL A cAMP/PKA/Kinesin-1 Axis Promotes the Axonal Transport of Mitochondria in Aging Drosophila Neurons. Curr Biol 28:1265-1272.e4 (2018). WB ; Drosophila melanogaster . PubMed: 29606421
  • Chuaijit S  et al. Identification of a novel mitochondrial complex I assembly factor ACDH-12 in Caenorhabditis elegans. Mitochondrion N/A:N/A (2018). PubMed: 29540318
  • Pashkovskaia N  et al. Mitochondrial ROS direct the differentiation of murine pluripotent P19 cells. Stem Cell Res 30:180-191 (2018). PubMed: 29957443
  • Wang L  et al. Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles. Cell Metab 28:400-414.e8 (2018). PubMed: 30017354
  • Collins CM  et al. ATP synthase F1 subunits recruited to centromeres by CENP-A are required for male meiosis. Nat Commun 9:2702 (2018). PubMed: 30006572
  • Seong E  et al. Mutations in VPS13D lead to a new recessive ataxia with spasticity and mitochondrial defects. Ann Neurol 83:1075-1088 (2018). PubMed: 29604224
  • Lin G  et al. Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to a-Synuclein Gain. Cell Metab N/A:N/A (2018). PubMed: 29909971
  • Ding L  et al. Seipin regulates lipid homeostasis by ensuring calcium-dependent mitochondrial metabolism. EMBO J 37:N/A (2018). PubMed: 30049710
  • Kelly AC  et al. Adrenergic receptor stimulation suppresses oxidative metabolism in isolated rat islets and Min6 cells. Mol Cell Endocrinol 473:136-145 (2018). WB . PubMed: 29360563
  • Kucherenko MM & Shcherbata HR Stress-dependent miR-980 regulation of Rbfox1/A2bp1 promotes ribonucleoprotein granule formation and cell survival. Nat Commun 9:312 (2018). Drosophila melanogaster . PubMed: 29358748
  • Kauppila JHK  et al. Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res N/A:N/A (2018). WB . PubMed: 29860357
  • Zagnoli-Vieira G  et al. Confirming TDP2 mutation in spinocerebellar ataxia autosomal recessive 23 (SCAR23). Neurol Genet 4:e262 (2018). PubMed: 30109272
  • Turner N  et al. A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism. Nat Commun 9:3165 (2018). PubMed: 30131496
  • Shanmughapriya S  et al. FOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiation. Nat Commun 9:3449 (2018). PubMed: 30158529
  • Lobo-Jarne T  et al. Human COX7A2L Regulates Complex III Biogenesis and Promotes Supercomplex Organization Remodeling without Affecting Mitochondrial Bioenergetics. Cell Rep 25:1786-1799.e4 (2018). PubMed: 30428348
  • Hermle T  et al. Modeling Monogenic Human Nephrotic Syndrome in the Drosophila Garland Cell Nephrocyte. J Am Soc Nephrol 28:1521-1533 (2017). PubMed: 27932481
  • Yoon WH  et al. Loss of Nardilysin, a Mitochondrial Co-chaperone for a-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. Neuron 93:115-131 (2017). PubMed: 28017472
  • Cuillerier A  et al. Loss of hepatic LRPPRC alters mitochondrial bioenergetics, regulation of permeability transition and trans-membrane ROS diffusion. Hum Mol Genet 26:3186-3201 (2017). PubMed: 28575497
  • Zhang C  et al. Incompatibility between mitochondrial and nuclear genomes during oogenesis results in ovarian failure and embryonic lethality. Development 144:2490-2503 (2017). PubMed: 28576772
  • Campos JC  et al. Exercise reestablishes autophagic flux and mitochondrial quality control in heart failure. Autophagy 13:1304-1317 (2017). PubMed: 28598232
  • Feichtinger RG  et al. Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies. Am J Hum Genet 101:525-538 (2017). PubMed: 28942965
  • Cracan V  et al. A genetically encoded tool for manipulation of NADP+/NADPH in living cells. Nat Chem Biol 13:1088-1095 (2017). WB . PubMed: 28805804
  • Binek A  et al. Proteomic footprint of myocardial ischemia/reperfusion injury: Longitudinal study of the at-risk and remote regions in the pig model. Sci Rep 7:12343 (2017). WB ; Pig . PubMed: 28955040
  • Song W  et al. Activin signaling mediates muscle-to-adipose communication in a mitochondria dysfunction-associated obesity model. Proc Natl Acad Sci U S A N/A:N/A (2017). PubMed: 28739899
  • Lin H  et al. Early VGLUT1-specific parallel fiber synaptic deficits and dysregulated cerebellar circuit in the KIKO mouse model of Friedreich ataxia. Dis Model Mech 10:1529-1538 (2017). PubMed: 29259026
  • Brüggemann M  et al. Systematic Analysis of the Expression of the Mitochondrial ATP Synthase (Complex V) Subunits in Clear Cell Renal Cell Carcinoma. Transl Oncol 10:661-668 (2017). WB ; Human . PubMed: 28672194
  • Greggio C  et al. Enhanced Respiratory Chain Supercomplex Formation in Response to Exercise in Human Skeletal Muscle. Cell Metab 25:301-311 (2017). WB ; Human . PubMed: 27916530
  • Shi G & McQuibban GA The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism. Cell Rep 18:1458-1472 (2017). PubMed: 28178523
  • Beutner G  et al. Cyclophilin D regulates the dynamic assembly of mitochondrial ATP synthase into synthasomes. Sci Rep 7:14488 (2017). PubMed: 29101324
  • Li C  et al. Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome. Nat Commun 8:1257 (2017). PubMed: 29097652
  • Liu Y  et al. Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells. Nat Commun 8:1212 (2017). PubMed: 29089484
  • Sha L  et al. Asymmetric Arginine Dimethylation Modulates Mitochondrial Energy Metabolism and Homeostasis in Caenorhabditis elegans. Mol Cell Biol 37:N/A (2017). PubMed: 27994012
  • Perks KL  et al. Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv 3:e1700677 (2017). PubMed: 28835921
  • Cohen J  et al. Astrocyte Senescence and Metabolic Changes in Response to HIV Antiretroviral Therapy Drugs. Front Aging Neurosci 9:281 (2017). PubMed: 28900395
  • Shneyer BI  et al. ROS induced distribution of mitochondria to filopodia by Myo19 depends on a class specific tryptophan in the motor domain. Sci Rep 7:11577 (2017). PubMed: 28912530
  • Gonzalez KL  et al. Disparate peroxisome-related defects in Arabidopsis pex6 and pex26 mutants link peroxisomal retrotranslocation and oil body utilization. Plant J 92:110-128 (2017). PubMed: 28742939
  • Theisen BE  et al. Deficiency of WARS2, encoding mitochondrial tryptophanyl tRNA synthetase, causes severe infantile onset leukoencephalopathy. Am J Med Genet A 173:2505-2510 (2017). PubMed: 28650581
  • Bick AG  et al. Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter. Proc Natl Acad Sci U S A 114:E9096-E9104 (2017). WB ; Mouse . PubMed: 29073106
  • Boutant M  et al. Mfn2 is critical for brown adipose tissue thermogenic function. EMBO J 36:1543-1558 (2017). PubMed: 28348166
  • Patrinostro X  et al. Relative importance of ßcyto- and ?cyto-actin in primary mouse embryonic fibroblasts. Mol Biol Cell 28:771-782 (2017). PubMed: 28077619
  • Zhang T  et al. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Sci Rep 7:45626 (2017). PubMed: 28378742
  • Schatton D  et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol 216:675-693 (2017). WB ; Mouse . PubMed: 28188211
  • Gómez-Serrano M  et al. Differential proteomic and oxidative profiles unveil dysfunctional protein import to adipocyte mitochondria in obesity-associated aging and diabetes. Redox Biol 11:415-428 (2017). WB ; Human . PubMed: 28064117
  • Jiang YF  et al. Electron tomographic analysis reveals ultrastructural features of mitochondrial cristae architecture which reflect energetic state and aging. Sci Rep 7:45474 (2017). WB . PubMed: 28358017
  • Antonicka H  et al. A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability. EMBO Rep 18:28-38 (2017). PubMed: 27974379
  • Gonzalez-Hurtado E  et al. Loss of macrophage fatty acid oxidation does not potentiate systemic metabolic dysfunction. Am J Physiol Endocrinol Metab 312:E381-E393 (2017). PubMed: 28223293
  • Sawyer EM  et al. Testis-specific ATP synthase peripheral stalk subunits required for tissue-specific mitochondrial morphogenesis in Drosophila. BMC Cell Biol 18:16 (2017). PubMed: 28335714
  • Maio N  et al. A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III. Cell Metab 25:945-953.e6 (2017). PubMed: 28380382
  • Heden TD  et al. Greater Oxidative Capacity in Primary Myotubes from Endurance-trained Women. Med Sci Sports Exerc 49:2151-2157 (2017). PubMed: 28617704
  • Chen JV  et al. A Splice Variant of Centrosomin Converts Mitochondria to Microtubule-Organizing Centers. Curr Biol 27:1928-1940.e6 (2017). PubMed: 28669756
  • Choi S  et al. Mitochondrial calcium uniporter in Drosophila transfers calcium between the endoplasmic reticulum and mitochondria in oxidative stress-induced cell death. J Biol Chem 292:14473-14485 (2017). PubMed: 28726639
  • Kayser EB  et al. Region-Specific Defects of Respiratory Capacities in the Ndufs4(KO) Mouse Brain. PLoS One 11:e0148219 (2016). WB . PubMed: 26824698
  • Thompson K  et al. Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number. Am J Hum Genet 99:860-876 (2016). PubMed: 27693233
  • Liu D  et al. Activation of mTORC1 is essential for ß-adrenergic stimulation of adipose browning. J Clin Invest 126:1704-16 (2016). PubMed: 27018708
  • Aguilera-Gomez A  et al. In vivo vizualisation of mono-ADP-ribosylation by dPARP16 upon amino-acid starvation. Elife 5:N/A (2016). ICC/IF ; Drosophila melanogaster . PubMed: 27874829
  • Luo B  et al. ATP-Dependent Lon Protease Contributes to Helicobacter pylori-Induced Gastric Carcinogenesis. Neoplasia 18:242-52 (2016). PubMed: 27108387
  • Sen A & Cox RT Clueless is a conserved ribonucleoprotein that binds the ribosome at the mitochondrial outer membrane. Biol Open 5:195-203 (2016). IHC ; Drosophila melanogaster . PubMed: 26834020
  • De La Fuente S  et al. Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle. J Biol Chem 291:23343-23362 (2016). PubMed: 27637331
  • Li HB  et al. Mitochondrial Ribosomal Protein L10 Associates with Cyclin B1/Cdk1 Activity and Mitochondrial Function. DNA Cell Biol 35:680-690 (2016). Human . PubMed: 27726420
  • Guarani V  et al. QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease. Elife 5:N/A (2016). PubMed: 27623147
  • Yu H  et al. Capitalizing Resolving Power of Density Gradient Ultracentrifugation by Freezing and Precisely Slicing Centrifuged Solution: Enabling Identification of Complex Proteins from Mitochondria by Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. J Anal Methods Chem 2016:8183656 (2016). WB ; Human . PubMed: 27668122
  • Ludtmann MH  et al. Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase. J Neurosci 36:10510-10521 (2016). WB ; Rat . PubMed: 27733604
  • Bowman CE  et al. Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series. Mol Cell Biol 36:2089-104 (2016). WB ; Mouse . PubMed: 27215380
  • Helman A  et al. p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion. Nat Med N/A:N/A (2016). IHC ; Human . PubMed: 26950362
  • Sakakibara I  et al. Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle. Skelet Muscle 6:30 (2016). WB ; Mouse . PubMed: 27597886
  • Vedelek V  et al. Testis-Specific Bb8 Is Essential in the Development of Spermatid Mitochondria. PLoS One 11:e0161289 (2016). PubMed: 27529784
  • Pérez-Pérez R  et al. COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation. Cell Rep 16:2387-98 (2016). ICC/IF . PubMed: 27545886
  • Seiferling D  et al. Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep 17:953-64 (2016). PubMed: 27154400
  • Peyta L  et al. Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells. Biochim Biophys Acta 1857:443-53 (2016). PubMed: 26768115
  • Schubert C  et al. Reduction of apoptosis and preservation of mitochondrial integrity under ischemia/reperfusion injury is mediated by estrogen receptor ß. Biol Sex Differ 7:53 (2016). PubMed: 27688871
  • Wrobel L  et al. The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly. Sci Rep 6:27484 (2016). PubMed: 27265872
  • Ponnalagu D  et al. Data supporting characterization of CLIC1, CLIC4, CLIC5 and DmCLIC antibodies and localization of CLICs in endoplasmic reticulum of cardiomyocytes. Data Brief 7:1038-44 (2016). PubMed: 27104215
  • Xie C  et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy 12:410-23 (2016). WB . PubMed: 26727396
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  • Janer A  et al. SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome. EMBO Mol Med 8:1019-38 (2016). PubMed: 27390132
  • McDonnell MM  et al. The Early-Acting Peroxin PEX19 Is Redundantly Encoded, Farnesylated, and Essential for Viability in Arabidopsis thaliana. PLoS One 11:e0148335 (2016). PubMed: 26824478
  • Shneyer BI  et al. Myo19 is an outer mitochondrial membrane motor and effector of starvation-induced filopodia. J Cell Sci 129:543-56 (2016). PubMed: 26659663
  • Casey JP  et al. Periventricular Calcification, Abnormal Pterins and Dry Thickened Skin: Expanding the Clinical Spectrum of RMND1? JIMD Rep 26:13-9 (2016). PubMed: 26238252
  • Lim SC  et al. Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly. FASEB J 30:2236-48 (2016). PubMed: 26929434
  • Burridge PW  et al. Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity. Nat Med 22:547-56 (2016). PubMed: 27089514
  • Hwang HJ  et al. Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome. Toxicol Appl Pharmacol 304:121-32 (2016). PubMed: 27105554
  • Yang H  et al. Adipose-Specific Deficiency of Fumarate Hydratase in Mice Protects Against Obesity, Hepatic Steatosis, and Insulin Resistance. Diabetes 65:3396-3409 (2016). PubMed: 27554470
  • Kluckova K  et al. Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation. Cell Death Dis 6:e1749 (2015). WB . PubMed: 25950479
  • Cui XA  et al. mRNA encoding Sec61ß, a tail-anchored protein, is localized on the endoplasmic reticulum. J Cell Sci 128:3398-410 (2015). IF . PubMed: 26272916
  • Vertii A  et al. Centrosome-intrinsic mechanisms modulate centrosome integrity during fever. Mol Biol Cell 26:3451-63 (2015). PubMed: 26269579
  • Jahani-Asl A  et al. CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death. Hum Mol Genet 24:4573-83 (2015). PubMed: 26002103
  • Sen A  et al. Clueless, a protein required for mitochondrial function, interacts with the PINK1-Parkin complex in Drosophila. Dis Model Mech 8:577-89 (2015). PubMed: 26035866
  • Nordby P  et al. Independent effects of endurance training and weight loss on peak fat oxidation in moderately overweight men: a randomized controlled trial. J Appl Physiol (1985) 118:803-10 (2015). PubMed: 25614598
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  • Zhu M  et al. Mask loss-of-function rescues mitochondrial impairment and muscle degeneration of Drosophila pink1 and parkin mutants. Hum Mol Genet 24:3272-85 (2015). PubMed: 25743185
  • Wang ZH  et al. Loss of a Clueless-dGRASP complex results in ER stress and blocks Integrin exit from the perinuclear endoplasmic reticulum in Drosophila larval muscle. Biol Open 4:636-48 (2015). ICC/IF ; Drosophila melanogaster . PubMed: 25862246
  • Gouspillou G  et al. Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle. Sci Rep 5:8717 (2015). WB ; Mouse . PubMed: 25732599
  • Peng M  et al. Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease. Hum Mol Genet 24:4829-47 (2015). WB . PubMed: 26041819
  • Cagin U  et al. Mitochondrial retrograde signaling regulates neuronal function. Proc Natl Acad Sci U S A 112:E6000-9 (2015). PubMed: 26489648
  • Alston CL  et al. A recessive homozygous p.Asp92Gly SDHD mutation causes prenatal cardiomyopathy and a severe mitochondrial complex II deficiency. Hum Genet 134:869-79 (2015). PubMed: 26008905
  • Liao X  et al. Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis. J Clin Invest 125:3461-76 (2015). PubMed: 26241060
  • Vincent G  et al. Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training. Front Physiol 6:51 (2015). WB . PubMed: 25759671
  • Teixeira FK  et al. ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation. Nat Cell Biol 17:689-96 (2015). PubMed: 25915123
  • Nordsborg NB  et al. Oxidative capacity and glycogen content increase more in arm than leg muscle in sedentary women after intense training. J Appl Physiol (1985) 119:116-23 (2015). PubMed: 26023221
  • Guarani V  et al. QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology. Elife 4:N/A (2015). PubMed: 25997101
  • Kao YT & Bartel B Elevated growth temperature decreases levels of the PEX5 peroxisome-targeting signal receptor and ameliorates defects of Arabidopsis mutants with an impaired PEX4 ubiquitin-conjugating enzyme. BMC Plant Biol 15:224 (2015). WB . PubMed: 26377801
  • Kopajtich R  et al. Mutations in GTPBP3 cause a mitochondrial translation defect associated with hypertrophic cardiomyopathy, lactic acidosis, and encephalopathy. Am J Hum Genet 95:708-20 (2014). PubMed: 25434004
  • Caro AA  et al. N-acetylcysteine inhibits the up-regulation of mitochondrial biogenesis genes in livers from rats fed ethanol chronically. Alcohol Clin Exp Res 38:2896-906 (2014). PubMed: 25581647
  • Vega-Naredo I  et al. Mitochondrial metabolism directs stemness and differentiation in P19 embryonal carcinoma stem cells. Cell Death Differ : (2014). PubMed: 24832466
  • Weng Z  et al. Green tea epigallocatechin gallate binds to and inhibits respiratory complexes in swelling but not normal rat hepatic mitochondria. Biochem Biophys Res Commun 443:1097-104 (2014). Rat . PubMed: 24384371
  • Scott I  et al. GCN5-like protein 1 (GCN5L1) controls mitochondrial content through coordinated regulation of mitochondrial biogenesis and mitophagy. J Biol Chem 289:2864-72 (2014). WB ; Mouse . PubMed: 24356961
  • Nilsson R  et al. Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer. Nat Commun 5:3128 (2014). WB ; Human . PubMed: 24451681
  • Jannig PR  et al. Autophagy signaling in skeletal muscle of infarcted rats. PLoS One 9:e85820 (2014). WB ; Rat . PubMed: 24427319
  • Kuang C  et al. A novel fizzy/Cdc20-dependent mechanism suppresses necrosis in neural stem cells. Development 141:1453-64 (2014). Drosophila melanogaster . PubMed: 24598157
  • Khacho M  et al. Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival. Nat Commun 5:3550 (2014). WB ; Mouse . PubMed: 24686499
  • Strittmatter L  et al. CLYBL is a polymorphic human enzyme with malate synthase and ß-methylmalate synthase activity. Hum Mol Genet 23:2313-23 (2014). PubMed: 24334609
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