Overview

  • Product name

  • Description

    Rabbit polyclonal to ATP6V0C
  • Host species

    Rabbit
  • Specificity

    This ATP6V0C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-126 amino acids from the C-terminal region of human ATP6V0C.
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Sheep, Cow
  • Immunogen

    Synthetic peptide corresponding to Human ATP6V0C aa 100-126.
    Sequence:

    GLSGLAAGFAIGIVGDAGVRGTAQQPR


    Database link: P27449

  • Positive control

    • IHC-P: Human kidney tissue. WB: NIH-3T3 whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab230323 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 16 kDa.
IHC-P 1/100.

Target

  • Relevance

    ATP6V0C is a component of the V0 domain (proton pore complex) of vacuolar ATPase (V-ATPase). Vacuolar ATPase is a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.
  • Cellular localization

    Vacuole membrane; Multi-pass membrane protein.
  • Database links

  • Alternative names

    • ATP6C antibody
    • ATP6L antibody
    • ATPase, H+ transporting, lysosomal, V0 subunit c antibody
    • ATPL antibody
    • V ATPase subunit c antibody
    • Vacuolar ATP synthase 16 kDa proteolipid subunit antibody
    • Vacuolar H+ ATPase proton channel subunit antibody
    • Vacuolar proton pump, 16 kDa subunit antibody
    • VATL antibody
    • Vma3 antibody
    see all

Images

  • Anti-ATP6V0C antibody (ab230323) at 1/1000 dilution + NIH-3T3 (mouse embryo fibroblast cell line) whole cell lysate at 35 µg

    Predicted band size: 16 kDa

  • Formalin-fixed, paraffin-embedded human kidney tissue stained for ATP6V0C using ab230323 at 1/100 dilution in immunohistochemical analysis.

References

ab230323 has not yet been referenced specifically in any publications.

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