Atracurium besylate, neuromuscular blocking agent (ab142484)

Overview

  • Product name

    Atracurium besylate, neuromuscular blocking agent
  • Description

    Competitive neuromuscular blocking agent
  • Biological description

    Competitive neuromuscular blocking agent. Non-depolarizing with short duration of action.
  • Purity

    > 95%
  • CAS Number

    64228-81-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2,2'-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] dibenzenesulfonate
  • Molecular weight

    1243.49
  • Molecular formula

    C65H82N2O18S2
  • PubChem identifier

    47320
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Tuba Z  et al. Synthesis and structure-activity relationships of neuromuscular blocking agents. Curr Med Chem 9:1507-36 (2002). Read more (PubMed: 12171561) »
  • Shorten GD & Gibbs NM Dose-response relationship of atracurium besylate in the halothane-anaesthetised pig. Res Vet Sci 55:392-3 (1993). Read more (PubMed: 8284509) »
  • Hughes R & Chapple DJ The pharmacology of atracurium: a new competitive neuromuscular blocking agent. Br J Anaesth 53:31-44 (1981). Read more (PubMed: 6161627) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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