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Rabbit monoclonal [EPR8072(2)] to ATRIP
WB more details Unsuitable for:
Flow Cyt,IHC-P or IP
Mouse, Rat, Human
Synthetic peptide within Human ATRIP aa 200-300 (Cysteine residue). The exact sequence is proprietary.
Database link: Q8WXE1
PC-3, Hela, MCF-7 cell lysates; MCF-7 cells.
® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab ® patents
This product is a recombinant rabbit monoclonal antibody.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.01% Sodium azide Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100.
1/1000 - 1/5000. Predicted molecular weight: 86 kDa.
Is unsuitable for Flow Cyt,IHC-P or IP.
Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Belongs to the ATRIP family.
The EEXXXDDL motif is required for the interaction with catalytic subunit PRKDC and its recruitment to sites of DNA damage.
Phosphorylated by ATR.
Nucleus. Redistributes to discrete nuclear foci upon DNA damage.
Information by UniProt
ATM and Rad3 related interacting protein antibody
This product has been referenced in:
et al. Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet 10:e1004413 (2014).
Read more (PubMed: 24992337) »
See 1 Publication
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"