Overview

  • Product name

    Anti-ATRIP (phospho S68) antibody
    See all ATRIP primary antibodies
  • Description

    Rabbit polyclonal to ATRIP (phospho S68)
  • Host species

    Rabbit
  • Specificity

    ab182626 detects endogenous level of ATRIP only when phosphorylated at Serine 68.
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human ATRIP aa 66-70 (phospho S68) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Sequence:

    LAS(p)QA


    Database link: Q8WXE1

  • Positive control

    • 3T3 cell line lysate

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.4
    Preservative: 0.05% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride

    without Mg2+ and Ca2+
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab182626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 86 kDa.

Target

  • Function

    Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the ATRIP family.
  • Domain

    The EEXXXDDL motif is required for the interaction with catalytic subunit PRKDC and its recruitment to sites of DNA damage.
  • Post-translational
    modifications

    Phosphorylated by ATR.
  • Cellular localization

    Nucleus. Redistributes to discrete nuclear foci upon DNA damage.
  • Information by UniProt
  • Database links

  • Alternative names

    • AGS1 antibody
    • ATIP antibody
    • ATM and Rad3 related interacting protein antibody
    • ATM and Rad3-related-interacting protein antibody
    • ATR interacting protein antibody
    • ATR-interacting protein antibody
    • Atrip antibody
    • ATRIP_HUMAN antibody
    • DKFZp762J2115 antibody
    • FLJ12343 antibody
    • MGC20625 antibody
    • MGC21482 antibody
    • MGC26740 antibody
    see all

Images

  • All lanes : Anti-ATRIP (phospho S68) antibody (ab182626) at 1/500 dilution

    Lane 1 : Extracts from 3T3 cells with Antigen-specific peptide
    Lane 2 : Extracts from 3T3 cells

    Developed using the ECL technique.

    Predicted band size: 86 kDa

References

ab182626 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab182626.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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