Overview

  • Product name

  • Description

    Rabbit polyclonal to Attractin
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human Attractin (internal sequence). UniProt ID: O75882.
    Database link: NP_001193976

  • Positive control

    • Human thyroid cancer and gastric cancer tissues.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 50% Glycerol, 49% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab199113 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system.
  • Tissue specificity

    Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes.
  • Sequence similarities

    Contains 1 C-type lectin domain.
    Contains 1 CUB domain.
    Contains 1 EGF-like domain.
    Contains 6 Kelch repeats.
    Contains 2 laminin EGF-like domains.
    Contains 4 PSI domains.
  • Post-translational
    modifications

    Heavily glycosylated.
  • Cellular localization

    Secreted and Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ATRN antibody
    • ATRN_HUMAN antibody
    • attractin 2 antibody
    • Attractin antibody
    • DPPT L antibody
    • DPPT-L antibody
    • KIAA0548 antibody
    • Mahogany homolog antibody
    • mahogany protein antibody
    • Mahogany, mouse, homolog of antibody
    • MGCA antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling Attractin using ab199113 at a 1/30 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue labeling Attractin using ab199113 at a 1/30 dilution.

References

ab199113 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab199113.
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