Overview

  • Product name
    Aurintricarboxylic acid (ATA), Apoptosis inhibitor
  • Description
    Apoptosis inhibitor
  • Alternative names
    • ATA
  • Biological description
    Inhibits endonucleases and downstream apoptosis. Displays a multitude of biological activities including inhibition of protein-nucleic acid interactions and topisomerase II. Inhibits protein synthesis.
  • CAS Number
    4431-00-9
  • Chemical structure
    Chemical Structure

Properties

References

This product has been referenced in:
  • Chen CW  et al. Inhibition of cytokine-induced JAK-STAT signalling pathways by an endonuclease inhibitor aurintricarboxylic acid. Br J Pharmacol 137:1011-20 (2002). Read more (PubMed: 12429573) »
  • Benchokroun Y  et al. Aurintricarboxylic acid, a putative inhibitor of apoptosis, is a potent inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells. Biochem Pharmacol 49:305-13 (1995). Read more (PubMed: 7857317) »
  • González RG  et al. Mechanism of action of polymeric aurintricarboxylic acid, a potent inhibitor of protein--nucleic acid interactions. Biochemistry 19:4299-303 (1980). Read more (PubMed: 6158332) »
  • Stewart ML  et al. Aurintricarboxylic acid: inhibitor of initiation of protein synthesis. Proc Natl Acad Sci U S A 68:97-101 (1971). Read more (PubMed: 5276307) »

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