Anti-AUTS2 antibody [CL7084] (ab243036)
Key features and details
- Mouse monoclonal [CL7084] to AUTS2
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG2a
Overview
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Product name
Anti-AUTS2 antibody [CL7084]
See all AUTS2 primary antibodies -
Description
Mouse monoclonal [CL7084] to AUTS2 -
Host species
Mouse -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide within Human AUTS2 aa 1050-1150. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: Q8WXX7 -
Positive control
- IHC-P: Mouse embryo E14, mouse cerebellum and hippocampus tissue. WB: SCLC-21H cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Protein A purified -
Purification notes
Purified from TCS. -
Clonality
Monoclonal -
Clone number
CL7084 -
Isotype
IgG2a -
Research areas
Associated products
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Compatible Secondaries
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab243036 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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WB |
Use a concentration of 1 µg/ml.
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Notes |
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IHC-P
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
WB
Use a concentration of 1 µg/ml. |
Target
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Tissue specificity
Strongly expressed in brain, skeletal muscle and kidney. Also expressed in placenta, lung and leukocytes. -
Sequence similarities
Belongs to the AUTS2 family. - Information by UniProt
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Database links
- Entrez Gene: 26053 Human
- Entrez Gene: 319974 Mouse
- Omim: 607270 Human
- SwissProt: Q8WXX7 Human
- SwissProt: Q8VDM3 Mouse
- Unigene: 21631 Human
- Unigene: 712991 Human
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Alternative names
- Autism related protein 1 antibody
- Autism susceptibility candidate 2 antibody
- Autism susceptibility gene 2 protein antibody
see all
Images
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Paraffin-embedded mouse embryo E14 tissue stained for AUTS2 using ab243036 at 1/200 dilution in immunohistochemical analysis.
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Anti-AUTS2 antibody [CL7084] (ab243036) at 1 µg/ml + SCLC-21H cell lysate
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Paraffin-embedded mouse hippocampus tissue stained for AUTS2 using ab243036 at 1/200 dilution in immunohistochemical analysis.
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Paraffin-embedded mouse cerebellum tissue stained for AUTS2 using ab243036 at 1/200 dilution in immunohistochemical analysis.
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Paraffin-embedded mouse embryo E14 tissue stained for AUTS2 using ab243036 at 1/200 dilution in immunohistochemical analysis.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab243036 has been referenced in 2 publications.
- Ziffra RS et al. Single-cell epigenomics reveals mechanisms of human cortical development. Nature 598:205-213 (2021). PubMed: 34616060
- Bhaduri A et al. Cell stress in cortical organoids impairs molecular subtype specification. Nature 578:142-148 (2020). PubMed: 31996853