Key features and details
- Rabbit polyclonal to Avian Influenza A Neuraminidase - N-terminal
- Suitable for: ELISA
- Reacts with: Influenza A
- Isotype: IgG
Product nameAnti-Avian Influenza A Neuraminidase antibody - N-terminal
See all Avian Influenza A Neuraminidase primary antibodies
DescriptionRabbit polyclonal to Avian Influenza A Neuraminidase - N-terminal
Tested applicationsSuitable for: ELISAmore details
Species reactivityReacts with: Influenza A
Synthetic peptide corresponding to Avian Influenza A Neuraminidase (N terminal). (11 amino acid peptide from near the amino terminus of the H7N9 [Influenza A virus (A/Shanghai/02/2013(H7N9))] Neuraminidase protein).
Database link: AGL44440
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab191862 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use a concentration of 1 µg/ml.|
RelevanceCatalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication. Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors. May facilitate viral invasion of the upper airways by cleaving the sialic acid moities on the mucin of the airway epithelial cells. Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport. May additionally display a raft-association independent effect on budding. Plays a role in the determination of host range restriction on replication and virulence. Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
Cellular localizationCell Membrane; Virion membrane. Apical cell membrane; Single-pass type II membrane protein (By similarity).
- NA antibody
- Neuraminidase antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab191862 has not yet been referenced specifically in any publications.