• Product name
  • Description
    Rabbit polyclonal to AVPR V2
  • Host species
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Chimpanzee, Gorilla, Chinese hamster
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 200 - 300 of Human AVPR V2.

  • Positive control
    • This antibody gave a positive signal in HEK293 whole cell lysate as well as the following tissue lysates: Human Fetal Kidney and Mouse Kidney.


  • Form
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab109326 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 40,43 kDa (predicted molecular weight: 40 kDa).


  • Function
    Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
  • Tissue specificity
  • Involvement in disease
    Defects in AVPR2 are the cause of nephrogenic syndrome of inappropriate antidiuresis (NSIAD) [MIM:300539]. This disorder is characterized by an inability to excrete a free water load, with inappropriately concentrated urine and resultant hyponatremia, hypoosmolarity, and natriuresis.
    Defects in AVPR2 are the cause of diabetes insipidus nephrogenic X-linked (XNDI) [MIM:304800]; also known as diabetes insipidus nephrogenic type 1. XNDI is caused by the inability of the renal collecting ducts to absorb water in response to arginine vasopressin. It is characterized by excessive water drinking (polydypsia), excessive urine excretion (polyuria), persistent hypotonic urine, and hypokalemia.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADHR antibody
    • Antidiuretic hormone receptor antibody
    • Arginine vasopressin receptor 2 antibody
    • AVP R2 antibody
    • AVPR 2 antibody
    • AVPR V2 antibody
    • AVPR2 antibody
    • DI1 antibody
    • DIR 3 antibody
    • DIR antibody
    • DIR3 antibody
    • MGC126533 antibody
    • MGC138386 antibody
    • NDI antibody
    • Nephrogenic diabetes insipidus antibody
    • Renal type arginine vasopressin receptor antibody
    • Renal-type arginine vasopressin receptor antibody
    • V2 receptor antibody
    • V2R antibody
    • V2R_HUMAN antibody
    • Vasopressin V2 antibody
    • Vasopressin V2 receptor antibody
    see all


  • All lanes : Anti-AVPR V2 antibody (ab109326) at 1 µg/ml (Milk blocking - 5%)

    Lane 1 : Kidney (Human) Tissue Lysate - fetal normal tissue (ab30204)
    Lane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate

    Lysates/proteins at 20 µg per lane.

    All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size: 40 kDa
    Observed band size: 43 kDa (why is the actual band size different from the predicted?)
    Additional bands at: 26 kDa, 72 kDa, 90 kDa. We are unsure as to the identity of these extra bands.

    Exposure time: 20 minutes
  • Anti-AVPR V2 antibody (ab109326) at 1 µg/ml (Milk blocking - 3%) + Kidney (Mouse) Tissue Lysate at 20 µg

    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size: 40 kDa
    Observed band size: 40 kDa

    Exposure time: 12 minutes

    AVPR V2 contains a potential glycosylation site(SwissProt) which may explain the banding pattern observed.


ab109326 has not yet been referenced specifically in any publications.

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