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    avpr1b-antibody-ab116246.pdf

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Anti-AVPR1B antibody (ab116246)

  • Datasheet
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AVPR1B antibody (ab116246)

    Key features and details

    • Goat polyclonal to AVPR1B
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

    You may also be interested in

    Secondary
    Product image
    Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)

    View more associated products

    Overview

    • Product name

      Anti-AVPR1B antibody
      See all AVPR1B primary antibodies
    • Description

      Goat polyclonal to AVPR1B
    • Host species

      Goat
    • Tested applications

      Suitable for: IHC-Pmore details
    • Species reactivity

      Reacts with: Human
    • Immunogen

      Synthetic peptide:

      PRDLELADGEGTAE

      , corresponding to C terminal amino acids 407-420 of Human AVPR1B.
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
    • Positive control

      • Human anterior pituitary tissue
    • General notes

       This product was previously labelled as AVPR1B, Vasopressin V1b receptor

       

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
    • Storage buffer

      pH: 7.30
      Preservative: 0.02% Sodium azide
      Constituents: 99% Tris buffered saline, 0.5% BSA
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Neuroscience
      • Neurotransmission
      • Receptors / Channels
      • GPCR
      • More GPCR
      • Neuroscience
      • Neurology process
      • Neuroendocrinology
      • Oxytocin & Vasopressin
      • Neuroscience
      • Neurotransmission
      • Receptors / Channels
      • GPCR
      • Vasopressin receptor

    Associated products

    • Compatible Secondaries

      • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
      • Donkey Anti-Goat IgG H&L (HRP) (ab205723)
    • Isotype control

      • Goat IgG, polyclonal - Isotype Control (ab37373)

    Applications

    Our Abpromise guarantee covers the use of ab116246 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    IHC-P Use a concentration of 3.75 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

    Target

    • Function

      Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.
    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
    • Cellular localization

      Cell membrane.
    • Target information above from: UniProt accession P47901 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 553 Human
      • Omim: 600264 Human
      • SwissProt: P47901 Human
      • Unigene: 1372 Human
      • Alternative names

        • Antidiuretic hormone receptor 1b antibody
        • Antidiuretic hormone, receptor for, V1B antibody
        • Arginine vasopressin receptor 1B antibody
        • Arginine vasopressin receptor 3 antibody
        • AVPR V1b antibody
        • AVPR V3 antibody
        • Avpr1b antibody
        • AVPR3 antibody
        • Pituitary vasopressin receptor 3 antibody
        • V1bR antibody
        • V1BR_HUMAN antibody
        • Vasopressin V1b receptor antibody
        • Vasopressin V3 receptor antibody
        • VPR3 antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AVPR1B antibody (ab116246)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AVPR1B antibody (ab116246)
        ab116246, at 5 µg/ml, staining AVPR1B in formalin fixed, paraffin embedded Human anterior pituitary tissue by Immunohistochemistry. After incubation with the primary antibody, slides were incubated with biotinylated anti-goat IgG secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

      Protocols

      • Immunohistochemistry protocols

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
    • References (1)

      Publishing research using ab116246? Please let us know so that we can cite the reference in this datasheet.

      ab116246 has been referenced in 1 publication.

      • Yang J  et al. Role of Vasopressin Receptor 2 and 3 in ACTH-Secreting Tumors and their Potential Therapeutic Implications. Exp Clin Endocrinol Diabetes N/A:N/A (2019). PubMed: 30669168

      Customer reviews and Q&As

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      There are currently no Customer reviews or Questions for ab116246.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com

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