Key features and details
- Potent, selective Aurora B kinase inhibitor
- CAS Number: 722544-51-6
- Purity: > 99%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Product nameAZD1152-HQPA, Aurora B kinase inhibitor
DescriptionPotent, selective Aurora B kinase inhibitor
Biological descriptionPotent, selective Aurora B kinase inhibitor (IC50 = 0.37 nM). Induces apoptosis in vitro. Antitumor agent. Cell-permeable. Active in vitro and in vivo.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142049 has been referenced in 1 publication.
- Mitchell E et al. XMU-MP-1 induces growth arrest in a model human mini-organ and antagonises cell cycle-dependent paclitaxel cytotoxicity. Cell Div 15:11 (2020). PubMed: 32973917