Overview

  • Product name

    Azithromycin dihydrate, Macrolide antibiotic
  • Description

    Macrolide antibiotic
  • Biological description

    Macrolide antibiotic. Bacterial 50S ribosomal inhibitor. Inhibits translation, cell viability and growth rate of bacterial cells (IC50 = 0.4 μg/ml). Orally active against gram-negative and gram-positive bacteria.
  • CAS Number

    117772-70-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Champney WS & Miller M Inhibition of 50S ribosomal subunit assembly in Haemophilus influenzae cells by azithromycin and erythromycin. Curr Microbiol 44:418-24 (2002). Read more (PubMed: 12000992) »
  • Champney WS & Burdine R Macrolide antibiotics inhibit 50S ribosomal subunit assembly in Bacillus subtilis and Staphylococcus aureus. Antimicrob Agents Chemother 39:2141-4 (1995). Read more (PubMed: 8540733) »
  • Retsema J  et al. Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms. Antimicrob Agents Chemother 31:1939-47 (1987). Read more (PubMed: 2449865) »
  • Girard AE  et al. Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new macrolide with an extended half-life and excellent tissue distribution. Antimicrob Agents Chemother 31:1948-54 (1987). Read more (PubMed: 2830841) »

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