Recombinant
RabMAb

Recombinant Anti-Azurocidin antibody [EPR9502] (ab178678)

Overview

  • Product name

    Anti-Azurocidin antibody [EPR9502]
    See all Azurocidin primary antibodies
  • Description

    Rabbit monoclonal [EPR9502] to Azurocidin
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Human
    Does not react with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human Azurocidin aa 1-100 (Cysteine residue). The exact sequence is proprietary.
    Database link: P20160

  • Positive control

    • Human spleen and U937 lysates.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab178678 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Detects a band of approximately 26-33 kDa (predicted molecular weight: 26 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function

      This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.
    • Sequence similarities

      Belongs to the peptidase S1 family. Elastase subfamily.
      Contains 1 peptidase S1 domain.
    • Cellular localization

      Cytoplasmic granule. Cytoplasmic granules of neutrophils.
    • Information by UniProt
    • Database links

    • Alternative names

      • Azu 1 antibody
      • AZU1 antibody
      • Azurocidin antibody
      • CAP37 antibody
      • CAP7_HUMAN antibody
      • Cationic antimicrobial protein 37 antibody
      • Cationic antimicrobial protein CAP37 antibody
      • HBP antibody
      • Heparin binding protein antibody
      • Heparin-binding protein antibody
      • HUMAZUR antibody
      • Neutrophil azurocidin antibody
      see all

    Images

    • All lanes : Anti-Azurocidin antibody [EPR9502] (ab178678) at 1/1000 dilution

      Lane 1 : Human spleen lysate
      Lane 2 : U937 lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 26 kDa

    References

    ab178678 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab178678.
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