Recombinant
RabMAb

Anti-Azurocidin antibody [EPR9503] - BSA and Azide free (ab250556)

Overview

  • Product name
    Anti-Azurocidin antibody [EPR9503] - BSA and Azide free
    See all Azurocidin primary antibodies
  • Description
    Rabbit monoclonal [EPR9503] to Azurocidin - BSA and Azide free
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Azurocidin aa 100-200. The exact sequence is proprietary.
    Database link: P20160

  • General notes

    ab250556 is a PBS-only buffer format of ab181989. Please refer to ab181989 for recommended dilutions, protocols, and image data.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab250556 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Detects a band of approximately 27-33 kDa (predicted molecular weight: 26 kDa).
Flow Cyt Use at an assay dependent concentration.

Target

  • Function
    This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.
  • Sequence similarities
    Belongs to the peptidase S1 family. Elastase subfamily.
    Contains 1 peptidase S1 domain.
  • Cellular localization
    Cytoplasmic granule. Cytoplasmic granules of neutrophils.
  • Information by UniProt
  • Database links
  • Alternative names
    • Azu 1 antibody
    • AZU1 antibody
    • Azurocidin antibody
    • CAP37 antibody
    • CAP7_HUMAN antibody
    • Cationic antimicrobial protein 37 antibody
    • Cationic antimicrobial protein CAP37 antibody
    • HBP antibody
    • Heparin binding protein antibody
    • Heparin-binding protein antibody
    • HUMAZUR antibody
    • Neutrophil azurocidin antibody
    see all

References

ab250556 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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