Key features and details
- Mouse monoclonal [H74] to B7H4 - Low endotoxin, Azide free
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-B7H4 antibody [H74] - Low endotoxin, Azide free
See all B7H4 primary antibodies
DescriptionMouse monoclonal [H74] to B7H4 - Low endotoxin, Azide free
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Human
Full length protein corresponding to Human B7H4.
Database link: Q7Z7D3
- Transient Human B7H4 transfected 293T cells.
Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Concentration information loading...
PurityProtein G purified
Light chain typekappa
Our Abpromise guarantee covers the use of ab171280 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 0.125-0.25µg for 105-8 cells.
(in a final volume of 100 μl).
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
FunctionNegatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Tissue specificityOverexpressed in breast, ovarian, endometrial, renal cell (RCC) and non-small-cell lung cancers (NSCLC). Expressed on activated T- and B-cells, monocytes and dendritic cells, but not expressed in most normal tissues (at protein level). Widely expressed, including in kidney, liver, lung, ovary, placenta, spleen and testis.
Sequence similaritiesBelongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 2 Ig-like V-type (immunoglobulin-like) domains.
Cellular localizationCell membrane. Expressed at the cell surface. A soluble form has also been detected.
- Information by UniProt
- B7 family member, H4 antibody
- B7 H4 antibody
- B7 homolog 4 antibody
ab171280 has not yet been referenced specifically in any publications.