Key features and details
- Rabbit polyclonal to Baboon
- Suitable for: IP, WB
- Reacts with: Drosophila melanogaster
- Isotype: IgG
Product nameAnti-Baboon antibody
See all Baboon primary antibodies
DescriptionRabbit polyclonal to Baboon
SpecificityThe antibody is unique to Baboon protein.
Tested applicationsSuitable for: IP, WBmore details
Species reactivityReacts with: Drosophila melanogaster
- Drosophila melanogaster extracts.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Concentration information loading...
PurityImmunogen affinity purified
Purification notesPurified against immobilized antigen based affinity chromatography which yielded epitope specific antibodies.
Our Abpromise guarantee covers the use of ab14682 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceTransmembrane receptor Patched regulates several developmental processes in both invertebrates and vertebrates. In higher vertebrates the patched (Ptc) also acts as a tumor suppressor. The patched receptor signaling involves negatively regulating a GPCR, smoothened. The binding Hedgehog ligand to Ptc removes the negative interaction of Ptc, and allows the signaling by smoothened. It has been shown that during head morphogenesis in D. melanogaster, Ptc positively interacts with smoothened, which leads to stimulation of Activin type 1 receptor Baboon, and activation of cell proliferation in the eye antennal disc. The expression of activated Baboon in the Ptc domain in Ptc mutant background completely abolish the head developmental defects.
- ATR1 antibody
- AtrI antibody
- Bab antibody
ab14682 has been referenced in 1 publication.
- Lai YW et al. Drosophila microRNA-34 Impairs Axon Pruning of Mushroom Body ? Neurons by Downregulating the Expression of Ecdysone Receptor. Sci Rep 6:39141 (2016). PubMed: 28008974