Recombinant
RabMAb

Recombinant Anti-BAFF-R antibody [EPR10914] - BSA and Azide free (ab190659)

Overview

  • Product name

    Anti-BAFF-R antibody [EPR10914] - BSA and Azide free
    See all BAFF-R primary antibodies
  • Description

    Rabbit monoclonal [EPR10914] to BAFF-R - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-Pmore details
    Unsuitable for: Flow Cyt,IP or WB
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human BAFF-R. The exact sequence is proprietary.
    Database link: Q96RJ3

  • Positive control

    • Human colon and tonsil tissues; Raji cells.
  • General notes

    Ab190659 is the carrier-free version of ab168389. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab190659 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Monoclonal
  • Clone number

    EPR10914
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab190659 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
  • Application notes
    Is unsuitable for Flow Cyt,IP or WB.
  • Target

    • Function

      B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
    • Tissue specificity

      Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.
    • Involvement in disease

      Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) [MIM:613494]; also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
    • Sequence similarities

      Contains 1 TNFR-Cys repeat.
    • Cellular localization

      Membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • B cell activating factor receptor antibody
      • B-cell-activating factor receptor antibody
      • BAFF R antibody
      • BAFF receptor antibody
      • BAFF-R antibody
      • BAFFR antibody
      • BLyS receptor 3 antibody
      • BlySR3 antibody
      • BR 3 antibody
      • BR3 antibody
      • BROMIX antibody
      • CD 268 antibody
      • CD268 antibody
      • CD268 antigen antibody
      • CVID4 antibody
      • MGC138235 antibody
      • OTTHUMP00000028746 antibody
      • Prolixin antibody
      • TNFRSF 13C antibody
      • Tnfrsf13c antibody
      • TR13C_HUMAN antibody
      • Tumor necrosis factor receptor subunit member 13C antibody
      • Tumor necrosis factor receptor superfamily member 13C antibody
      see all

    References

    ab190659 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab190659.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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