Overview

  • Product name

  • Description

    Rabbit polyclonal to Bag5
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide derived from the human BAG5 protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab24314 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 5 - 10 µg/ml. Predicted molecular weight: 51 kDa.
IHC-P Use at an assay dependent concentration.

Target

  • Function

    Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.
  • Sequence similarities

    Contains 5 BAG domains.
  • Domain

    The fifth BAG domain is responsible for the interaction with HSP70 nucleotide-binding domain.
  • Information by UniProt
  • Database links

  • Alternative names

    • BAG family molecular chaperone regulator 5 antibody
    • BAG-5 antibody
    • BAG5 antibody
    • BAG5_HUMAN antibody
    • Bcl 2 associated athanogene 5 antibody
    • Bcl-2-associated athanogene 5 antibody
    • BCL2 associated athanogene 5 antibody
    • KIAA0873 antibody
    see all

References

This product has been referenced in:

  • Chen Y  et al. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. Mol Cell Proteomics 12:2804-19 (2013). Read more (PubMed: 23824909) »
See 1 Publication for this product

Customer reviews and Q&As

Abreviews
Application
Western blot
Sample
Human Cell lysate - whole cell (HEK293)
Loading amount
68 µg
Specification
HEK293
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 2%

Mr. Jörg Hoehfeld

Verified customer

Submitted Jan 03 2007

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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