Validated using a knockout cell line

Anti-Bak antibody [Y164] (ab32371)

Publishing research using ab32371? Please let us know so that we can cite the reference in this datasheet.

ab32371 has been referenced in 23 publications.

  • Liu C  et al. MiR-144-3p promotes the tumor growth and metastasis of papillary thyroid carcinoma by targeting paired box gene 8. Cancer Cell Int 18:54 (2018). WB ; Human . PubMed: 29632436
  • Ruvolo PP  et al. Role of MSC-derived galectin 3 in the AML microenvironment. Biochim Biophys Acta 1865:959-969 (2018). PubMed: 29655803
  • Holloway A  et al. Resistance to UV-induced apoptosis by ß-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase. Int J Cancer 136:2831-43 (2015). PubMed: 25408501
  • Lauf PK  et al. Interaction between Na-K-ATPase and Bcl-2 proteins BclXL and Bak. Am J Physiol Cell Physiol 308:C51-60 (2015). Human . PubMed: 25318106
  • Xiao Y  et al. MCL-1 Is a Key Determinant of Breast Cancer Cell Survival: Validation of MCL-1 Dependency Utilizing a Highly Selective Small Molecule Inhibitor. Mol Cancer Ther 14:1837-47 (2015). WB ; Human . PubMed: 26013319
  • Hearn JM  et al. Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells. Proc Natl Acad Sci U S A 112:E3800-5 (2015). Human . PubMed: 26162681
  • Wang B  et al. Role of Ku70 in deubiquitination of Mcl-1 and suppression of apoptosis. Cell Death Differ 21:1160-9 (2014). PubMed: 24769731
  • Hsu KH  et al. Anti-apoptotic effects of osteopontin through the up-regulation of Mcl-1 in gastrointestinal stromal tumors. World J Surg Oncol 12:189 (2014). WB ; Human . PubMed: 24947165
  • Sun Y  et al. Up-regulation of eEF1A2 promotes proliferation and inhibits apoptosis in prostate cancer. Biochem Biophys Res Commun 450:1-6 (2014). WB ; Human . PubMed: 24853801
  • Peng YF  et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy 9:2056-68 (2013). WB ; Human . PubMed: 24157892
  • Zhang Z  et al. An antiapoptotic Bcl-2 family protein index predicts the response of leukaemic cells to the pan-Bcl-2 inhibitor S1. Br J Cancer 108:1870-8 (2013). WB ; Human . PubMed: 23558901
  • Azad A & Storey A BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groove. Mol Cancer 12:65 (2013). WB . PubMed: 23782464
  • Azad A  et al. Blockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis. PLoS One 7:e49601 (2012). WB ; Human . PubMed: 23189150
  • Jin L  et al. Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma. Br J Cancer 104:91-100 (2011). Flow Cyt ; Human . PubMed: 21139584
  • Chan NC  et al. Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum Mol Genet 20:1726-37 (2011). WB ; Human . PubMed: 21296869
  • Shigematsu S  et al. ZNF689 suppresses apoptosis of hepatocellular carcinoma cells through the down-regulation of Bcl-2 family members. Exp Cell Res 317:1851-9 (2011). WB ; Human . PubMed: 21624362
  • Andrade D & Rosenblatt J Apoptotic regulation of epithelial cellular extrusion. Apoptosis 16:491-501 (2011). WB . PubMed: 21399977
  • Altonsy MO  et al. Differential induction of apoptosis in human colonic carcinoma cells (Caco-2) by Atopobium, and commensal, probiotic and enteropathogenic bacteria: mediation by the mitochondrial pathway. Int J Food Microbiol 137:190-203 (2010). WB ; Human . PubMed: 20036023
  • Ferreira IL  et al. Mitochondrial-dependent apoptosis in Huntington's disease human cybrids. Exp Neurol 222:243-55 (2010). WB ; Human . PubMed: 20079354
  • Fox JL  et al. Tyrosine dephosphorylation is required for Bak activation in apoptosis. EMBO J 29:3853-68 (2010). WB ; Human . PubMed: 20959805
  • Schache P  et al. VSV virotherapy improves chemotherapy by triggering apoptosis due to proteasomal degradation of Mcl-1. Gene Ther 16:849-61 (2009). WB ; Human . PubMed: 19369968
  • Greider CW Telomere length regulation. Annu Rev Biochem 65:337-65 (1996). PubMed: 8811183
  • Feng J  et al. The RNA component of human telomerase. Science 269:1236-41 (1995). PubMed: 7544491


Sign up