Key features and details
- Rabbit polyclonal to BANP
- Suitable for: IHC-P, ICC/IF, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-BANP antibody
See all BANP primary antibodies
DescriptionRabbit polyclonal to BANP
Tested applicationsSuitable for: IHC-P, ICC/IF, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to a 14 amino acid internal sequence of Human BANP (NP_001167014).
- Mouse kidney tissue lysate.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab105404 is purified by affinity chromatography via a peptide column.
Our Abpromise guarantee covers the use of ab105404 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.|
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa.|
FunctionControls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest.
Tissue specificityDown-regulated in breast cancer cell lines.
Sequence similaritiesBelongs to the BANP/SMAR1 family.
Contains 1 BEN domain.
- Information by UniProt
- AAH09424 antibody
- Banp antibody
- BANP_HUMAN antibody
Lane 1 : Anti-BANP antibody (ab105404) at 1 µg/ml
Lane 2 : Anti-BANP antibody (ab105404) at 2 µg/ml
All lanes : Mouse kidney tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 56 kDa
Immunofluorescence of BANP in Human kidney tissue with ab105404 at 20 ug/mL.
Immunohistochemistry of Human kidney tissue with ab105404 at 10 μg/mL.
ab105404 has been referenced in 1 publication.
- Chucair-Elliott AJ et al. Tamoxifen induction of Cre recombinase does not cause long-lasting or sexually divergent responses in the CNS epigenome or transcriptome: implications for the design of aging studies. Geroscience 41:691-708 (2019). PubMed: 31493147