Overview

  • Product name
    Anti-basic Cytokeratin antibody [AE3], prediluted
  • Description
    Mouse monoclonal [AE3] to basic Cytokeratin, prediluted
  • Host species
    Mouse
  • Specificity
    This antibody recognizes basic (Type II or HMW) cytokeratins, which includes 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). This antibody recognizes 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.
  • Tested applications
    Suitable for: IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Chicken, Cow, Human, Monkey
  • Immunogen

    BALB/C mice were immunized with human epidermal keratin.

Properties

Applications

Our Abpromise guarantee covers the use of ab870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

Target

  • Relevance
    In keratinized epidermis, 58 kD cytokeratin is present in the basal and suprabasal layers, while 65 to 67 kD cytokeratin is present in the cells above the basal layers.
  • Cellular localization
    Cytoplasmic. Intermediate filament.
  • Database links
  • Alternative names
    • 58 kDa cytokeratin antibody
    • 65 kDa cytokeratin antibody
    • CK3 antibody
    • CK4 antibody
    • CK5 antibody
    • CYK4 antibody
    • Cytokeratin-3 antibody
    • Cytokeratin-4 antibody
    • Cytokeratin-5 antibody
    • DDD antibody
    • EBS2 antibody
    • FLJ31692 antibody
    • FLJ95909 antibody
    • K3 antibody
    • K4 antibody
    • K5 antibody
    • Keratin 3 antibody
    • Keratin 4 antibody
    • Keratin 5 antibody
    • Keratin, type II cytoskeletal 3 antibody
    • Keratin, type II cytoskeletal 4 antibody
    • Keratin, type II cytoskeletal 5 antibody
    • KRT3 antibody
    • KRT4 antibody
    • KRT5 antibody
    • KRT5A antibody
    • Type-II keratin Kb3 antibody
    • Type-II keratin Kb4 antibody
    • Type-II keratin Kb5 antibody
    see all

References

This product has been referenced in:
  • Vidalain PO  et al. Interferons mediate terminal differentiation of human cortical thymic epithelial cells. J Virol 76:6415-24 (2002). Read more (PubMed: 12050353) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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