Key features and details
- Rabbit polyclonal to Bassoon/BSN
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-Bassoon/BSN antibody
See all Bassoon/BSN primary antibodies
DescriptionRabbit polyclonal to Bassoon/BSN
SpecificityNo cross-reactivity to Piccolo. Multiple isoforms can be detected.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Fusion protein corresponding to Human Bassoon/BSN aa 786-1041.
This product was previously labelled as Bassoon
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab110426 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.|
|WB||1/1000. Predicted molecular weight: 416 kDa. For large isoforms reduce dilution.|
FunctionIs thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses.
Tissue specificityExclusively expressed in brain.
modificationsMyristoylated. The N-terminal myristoylation is not sufficient for presynaptic localization.
Cellular localizationCytoplasm. Cell junction > synapse > synaptosome. Cytoplasm > cytoskeleton. Localized to the active zone of presynaptic density.
- Information by UniProt
- Bassoon protein antibody
- bsn antibody
- BSN_HUMAN antibody
All lanes : Anti-Bassoon/BSN antibody (ab110426) at 1/1000 dilution
Lane 1 : Rat brain lysate
Lane 2 : Mouse brain lysate
Lysates/proteins at 10 µg per lane.
Predicted band size: 416 kDa
Immunofluorescence of Neuromuscular junction whole muscle samples from adult mouse, stained with ab110426 at 1/400 dilution. Secondary (Alexa 488 goat antimouse IgG, IgM (H+L). Note: bright staining of the NMJ very selectively and in some terminals, very brightly.
ab110426 has been referenced in 1 publication.
- Guo N et al. Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization. Nat Med 24:438-449 (2018). PubMed: 29529016