Key features and details
- Potent, broad-spectrum MMP inhibitor
- CAS Number: 130370-60-4
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameBatimastat (BB-94), Matrix metalloprotease (MMP) inhibitor
DescriptionPotent, broad-spectrum MMP inhibitor
Potent, broad-spectrum MMP inhibitor (IC50 values are 3 (MMP-1), 4 (MMP-2), 4 (MMP-9), 6 (MMP-7), 20 nM (MMP-3)). Anticancer activity in vivo.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab142087 has been referenced in 5 publications.
- Ambite I et al. Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets. PLoS Pathog 12:e1005848 (2016). PubMed: 27732661
- Paschkowsky S et al. Alternative Processing of the Amyloid Precursor Protein Family by Rhomboid Protease RHBDL4. J Biol Chem 291:21903-21912 (2016). PubMed: 27563067
- McColl R et al. Analysis and quantification of in vitro myoblast fusion using the LADD Multiple Stain. Biotechniques 61:323-326 (2016). PubMed: 27938324
- Cremasco V et al. B cell homeostasis and follicle confines are governed by fibroblastic reticular cells. Nat Immunol 15:973-81 (2014). PubMed: 25151489
- Beltramo E et al. Extracellular vesicles derived from mesenchymal stem cells induce features of diabetic retinopathy in vitro. Acta Diabetol 51:1055-64 (2014). PubMed: 25374383