Overview

  • Product name

    Batimastat (BB-94), Matrix metalloprotease (MMP) inhibitor
  • Description

    Potent, broad-spectrum MMP inhibitor
  • Biological description

    Potent, broad-spectrum MMP inhibitor (IC50 values are 3 (MMP-1), 4 (MMP-2), 4 (MMP-9), 6 (MMP-7), 20 nM (MMP-3)). Anticancer activity in vivo.
  • Purity

    > 98%
  • CAS Number

    130370-60-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Lein M  et al. Synthetic inhibitor of matrix metalloproteinases (batimastat) reduces prostate cancer growth in an orthotopic rat model. Prostate 43:77-82 (2000). Read more (PubMed: 10754522) »
  • Botos I  et al. Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding. Proc Natl Acad Sci U S A 93:2749-54 (1996). Read more (PubMed: 8610113) »
  • Wang X  et al. Matrix metalloproteinase inhibitor BB-94 (batimastat) inhibits human colon tumor growth and spread in a patient-like orthotopic model in nude mice. Cancer Res 54:4726-8 (1994). Read more (PubMed: 8062271) »
See all 3 Publications for this product

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