Bax Channel Blocker, mitochondrial cytochrome c release inhibitor (ab145899)
Overview
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Product name
Bax Channel Blocker, mitochondrial cytochrome c release inhibitor -
Description
Bax-mediated mitochondrial cytochrome c release inhibitor -
Alternative names
- 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(piperazin-1-yl)propan-2-ol
- bis TFA
- iMAC1
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Biological description
Cell-permeable dibromocarbazolo-piperazinyl derivative that displays anti-apoptotic properties. Blocks Bid-induced cytochrome c release from HeLa cell mitochondria by inhibiting Bax channel forming activitiy.
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Purity
> 95% -
CAS Number
335165-69-9 -
Chemical structure
Properties
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Chemical name
1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(piperazin-1-yl)propan-2-ol trifluoroacetate -
Molecular weight
695.30 -
Molecular formula
C19H21Br2N3O.2CF3CO2H -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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Source
Synthetic
Associated products
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab145899 has not yet been referenced specifically in any publications.
