Overview

  • Product name

    BAY 11-7082, IkappaBalpha kinase inhibitor
  • Description

    IκBα kinase inhibitor. NF-κB inhibitor. Apoptosis inducer. Inhibits the release of proinflammatory cytokines. Inflammasome inhibitor. Platelet aggregation inhibitor.
  • Purity

    > 99%
  • CAS Number

    19542-67-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Jayakumar AR  et al. Activation of NF-?B mediates astrocyte swelling and brain edema in traumatic brain injury. J Neurotrauma 31:1249-57 (2014). Read more (PubMed: 24471369) »
  • Strickson S  et al. The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system. Biochem J 451:427-37 (2013). Read more (PubMed: 23441730) »
  • Rauert-Wunderlich H  et al. The IKK inhibitor Bay 11-7082 induces cell death independent from inhibition of activation of NF?B transcription factors. PLoS One 8:e59292 (2013). Read more (PubMed: 23527154) »
See all 2 Publications for this product

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