Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab21705 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.5 µg/ml.|
|ELISA||Use at an assay dependent dilution.|
FunctionMay act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins.
Tissue specificityUbiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue.
Sequence similaritiesContains 1 Ras-GEF domain.
Contains 1 SH2 domain.
- Information by UniProt
- BCAR 3 antibody
- BCAR3 antibody
- BCAR3_HUMAN antibody
ab21705 has not yet been referenced specifically in any publications.