Overview

  • Product name

    Anti-Bcl 7A antibody [15C]
    See all Bcl 7A primary antibodies
  • Description

    Mouse monoclonal [15C] to Bcl 7A
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-Pmore details
    Unsuitable for: Flow Cyt,ICC/IF,IP or WB
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment. This information is considered to be commercially sensitive.

  • Positive control

    • IHC-P: Human tonsil tissue.
  • General notes

    This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com.

Properties

Applications

Our Abpromise guarantee covers the use of ab241550 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IP or WB.
  • Target

    • Involvement in disease

      Note=Chromosomal aberrations involving BCL7A may be a cause of B-cell non-Hodgkin lymphoma. Three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with MYC and with immunoglobulin gene regions.
    • Sequence similarities

      Belongs to the BCL7 family.
    • Post-translational
      modifications

      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Information by UniProt
    • Database links

    • Alternative names

      • B cell CLL/lymphoma 7 antibody
      • B cell CLL/lymphoma 7 protein family member A antibody
      • B cell CLL/lymphoma 7A antibody
      • B-cell CLL/lymphoma 7 protein family member A antibody
      • BCL 7 antibody
      • BCL7 antibody
      • bcl7a antibody
      • BCL7A_HUMAN antibody
      see all

    Images

    • Immunohistochemical analysis of paraffin-embedded human tonsil tissue labeling Bcl 7A with ab241550 at 1/200 dilution, followed by Goat Anti-Mouse IgG H&L (HRP polymer) (ab214879) ready to use. Nuclear staining on the tonsil is observed. Counter stained with hematoxylin.

      Secondary antibody only control: Used PBS instead of primary antibody, secondary antibody Goat Anti-Mouse IgG H&L (HRP polymer) (ab214879) ready to use.

      Heat mediated antigen retrieval using ab93684 (Tris/EDTA buffer, pH 9.0).

      The section was incubated with ab241550 for 30 mins at room temperature.

      The immunostaining staining was performed on a Leica Biosystems BOND® RX instrument

    References

    ab241550 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab241550.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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